CASP8
| Description | Caspase-8 |
|---|
Gene and Protein Information
| Gene ID | 841 |
|---|---|
| Uniprot Accession IDs | O14676 Q14791 Q14792 Q14793 Q14794 Q14795 Q14796 Q15780 Q15806 Q53TT5 Q8TDI1 Q8TDI2 Q8TDI3 Q8TDI4 Q8TDI5 Q96T22 Q9C0K4 Q9UQ81 CASP-8 |
| Ensembl ID | ENSP00000351273 |
| Symbol | MCH5 CAP4 MACH MCH5 FLICE ALPS2B Casp-8 |
| Family | Belongs to the peptidase C14A family. |
| Sequence | MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 746477 | CASP8 | caspase 8 | 9598 | VGNC:119 | OMA, EggNOG |
| Macaque | 702781 | CASP8 | caspase 8 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 12370 | Casp8 | caspase 8 | 10090 | MGI:1261423 | Inparanoid, OMA, EggNOG |
| Rat | 64044 | Casp8 | caspase 8 | 10116 | RGD:620945 | Inparanoid, OMA, EggNOG |
| Dog | 488473 | CASP8 | caspase 8 | 9615 | VGNC:38736 | Inparanoid, OMA, EggNOG |
| Horse | 100066502 | CASP8 | caspase 8 | 9796 | VGNC:16071 | Inparanoid, OMA, EggNOG |
| Cow | 507481 | CASP8 | caspase 8 | 9913 | VGNC:26784 | Inparanoid, OMA, EggNOG |
| Opossum | 100617599 | LOC100617599 | caspase-8 | 13616 | OMA, EggNOG | |
| Platypus | CASP8 | caspase 8 [Source:HGNC Symbol;Acc:HGNC:1509] | 9258 | OMA, EggNOG | ||
| Chicken | 395284 | CASP8 | caspase 8 | 9031 | CGNC:6332 | Inparanoid, OMA |
| Zebrafish | 58022 | casp8 | caspase 8, apoptosis-related cysteine peptidase | 7955 | ZDB-GENE-000713-1 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / enzyme modulator / protease inhibitor / Caspase-8
protein / enzyme modulator / cysteine protease / Caspase-8
protein / enzyme modulator / protease / Caspase-8
protein / enzyme modulator / hydrolase / Caspase-8
protein / enzyme modulator / protease inhibitor / Caspase-8
protein / enzyme modulator / cysteine protease / Caspase-8
protein / enzyme modulator / protease / Caspase-8
protein / enzyme modulator / hydrolase / Caspase-8
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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