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HSD11B1
| Description | Corticosteroid 11-beta-dehydrogenase isozyme 1 |
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Gene and Protein Information
| Gene ID | 3290 |
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| Uniprot Accession IDs | B2R9Z1 D3DT89 |
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| Ensembl ID | ENSP00000355995 |
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| Symbol | HSD11 HSD11L SDR26C1 HDL 11-DH HSD11 HSD11B HSD11L CORTRD2 SDR26C1 11-beta-HSD1 |
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| Family | Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
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| Sequence | MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 457698 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 | 9598 | VGNC:11453 | OMA, EggNOG |
| Mouse | 15483 | Hsd11b1 | hydroxysteroid 11-beta dehydrogenase 1 | 10090 | MGI:103562 | Inparanoid, OMA, EggNOG |
| Rat | 25116 | Hsd11b1 | hydroxysteroid 11-beta dehydrogenase 1 | 10116 | RGD:2834 | Inparanoid, OMA |
| Dog | 449023 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 | 9615 | VGNC:41797 | Inparanoid, OMA, EggNOG |
| Horse | 100056429 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 | 9796 | VGNC:18880 | Inparanoid, OMA, EggNOG |
| Cow | 282589 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 | 9913 | VGNC:29965 | Inparanoid, OMA, EggNOG |
| Pig | 397480 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 | 9823 | | Inparanoid, OMA, EggNOG |
| Platypus | 100079059 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 | 9258 | | Inparanoid, OMA, EggNOG |
| Anole lizard | 100555338 | hsd11b1 | hydroxysteroid 11-beta dehydrogenase 1 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100489345 | hsd11b1 | hydroxysteroid (11-beta) dehydrogenase 1 | 8364 | XB-GENE-960491 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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