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CYP2C9

DescriptionCytochrome P450 2C9

Gene and Protein Information

Gene ID1559
Uniprot Accession IDs P11713 Q16756 Q16872 Q5VX92 Q6IRV8 Q8WW80
Ensembl ID ENSP00000260682
Symbol CYP2C10 CPC9 CYP2C CYP2C10 CYPIIC9 P450IIC9
FamilyBelongs to the cytochrome P450 family.
Sequence
MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp100616515CYP2C9cytochrome P450 family 2 subfamily C member 99598VGNC:6151OMA, EggNOG
Macaque678686CYP2C75cytochrome P450, family 2, subfamily C, polypeptide 759544Inparanoid, OMA
Horse100071061LOC100071061cytochrome P450 2C42-like9796Inparanoid, OMA

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details
Recombinant CYP2C9 AntibodyHuman
  • WB
Out of Stock
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Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      Bibliography

      1.Aithal, G P GP, Day, C P CP, Kesteven, P J PJ and Daly, A K AK. 1999-02-27 Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications. [PMID:10073515]
      2.Finta, C C and Zaphiropoulos, P G PG. 2000-02-01 The human CYP2C locus: a prototype for intergenic and exon repetition splicing events. [PMID:10704292]
      3.Imai, J J and 11 more authors. 2000-02 Polymorphism of the cytochrome P450 (CYP) 2C9 gene in Japanese epileptic patients: genetic analysis of the CYP2C9 locus. [PMID:10739176]
      4.Margaglione, M M and 6 more authors. 2000-11 Genetic modulation of oral anticoagulation with warfarin. [PMID:11127854]
      5.Pirmohamed, M M and 6 more authors. 2000-11 Association analysis of drug metabolizing enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole hypersensitivity. [PMID:11186133]
      6.Yoon, Y R YR and 7 more authors. 2001-03 Frequency of cytochrome P450 2C9 mutant alleles in a Korean population. [PMID:11298075]
      7.Bigler, J J and 5 more authors. 2001-05-01 CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk. [PMID:11325819]
      8.García-Martín, E E, Martínez, C C, Ladero, J M JM, Gamito, F J FJ and Agúndez, J A JA. 2001-04 High frequency of mutations related to impaired CYP2C9 metabolism in a Caucasian population. [PMID:11372590]
      9. and Henderson, R F RF. 2001-06-01 Species differences in the metabolism of olefins: implications for risk assessment. [PMID:11397381]
      10.Martin, J H JH, Begg, E J EJ, Kennedy, M A MA, Roberts, R R and Barclay, M L ML. 2001-06 Is cytochrome P450 2C9 genotype associated with NSAID gastric ulceration? [PMID:11422024]