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MS4A1

DescriptionB-lymphocyte antigen CD20

Gene and Protein Information

Gene ID931
Uniprot Accession IDs P11836 A6NMS4 B4DT24 P08984 Q13963
Ensembl ID ENSP00000433277
Symbol CD20 B1 S7 Bp35 CD20 CVID5 MS4A2 LEU-16
FamilyBelongs to the MS4A family.
Sequence
MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp451223MS4A1membrane spanning 4-domains A19598VGNC:7669OMA, EggNOG
Macaque696843MS4A1membrane spanning 4-domains A19544Inparanoid, OMA, EggNOG
Mouse12482Ms4a1membrane-spanning 4-domains, subfamily A, member 110090MGI:88321Inparanoid, OMA, EggNOG
Rat309217Ms4a1membrane spanning 4-domains A110116RGD:1311999Inparanoid, OMA, EggNOG
Dog485430MS4A1membrane spanning 4-domains A19615VGNC:52268Inparanoid, OMA, EggNOG
Horse100059000MS4A1membrane spanning 4-domains A19796VGNC:20376Inparanoid, OMA, EggNOG
Cow505653MS4A1membrane spanning 4-domains A19913VGNC:31681Inparanoid, OMA, EggNOG
Pig100627952MS4A1membrane spanning 4-domains A19823Inparanoid, OMA, EggNOG
Opossum100029355MS4A1membrane spanning 4-domains A113616Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    B-lymphocyte antigen CD20
DTO Classes
protein    /    Receptor    /    B-lymphocyte antigen CD20

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      Bibliography

      1.Yamanaka, T T and 5 more authors. 2001-01 M cell pockets of human Peyer's patches are specialized extensions of germinal centers. [PMID:11169444]
      2.Hong, Hai-Yan HY and 6 more authors. 2000 Cloning and Expression of Human CD20 Gene on NIH-3T3 Cell Membrane. [PMID:12075439]
      3.Macardle, P J PJ and Nicholson, I C IC.CD20. [PMID:12144126]
      4.Petrie, Ryan J RJ and Deans, Julie P JP. 2002-09-15 Colocalization of the B cell receptor and CD20 followed by activation-dependent dissociation in distinct lipid rafts. [PMID:12218101]
      5.Cragg, Mark S MS and 7 more authors. 2003-02-01 Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts. [PMID:12393541]
      6.Tamayose, Kenji K, Sato, Naotake N, Ando, Jun J, Sugimoto, Koichi K and Oshimi, Kazuo K. 2002-12 CD3-negative, CD20-positive T-cell prolymphocytic leukemia: case report and review of the literature. [PMID:12447967]
      7.Strausberg, Robert L RL and 83 more authors. 2002-12-24 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. [PMID:12477932]
      8.Sandilands, Gavin P GP and 7 more authors. 2003-03 Detection of cytoplasmic CD antigens within normal human peripheral blood leucocytes. [PMID:12603599]
      9.Steiniger, Birte B, Rüttinger, Lars L and Barth, Peter J PJ. 2003-05 The three-dimensional structure of human splenic white pulp compartments. [PMID:12704213]
      10.Polyak, M J MJ, Ayer, L M LM, Szczepek, A J AJ and Deans, J P JP. 2003-07 A cholesterol-dependent CD20 epitope detected by the FMC7 antibody. [PMID:12835728]