SLC1A2

DescriptionExcitatory amino acid transporter 2

Gene and Protein Information

Gene ID6506
Uniprot Accession IDs B4DQE9 Q14417 Q541G6 U3KQQ4
Ensembl ID ENSP00000278379
Symbol EAAT2 GLT1 HBGT EAAT2 GLT-1 EIEE41
FamilyBelongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A2 subfamily.
Sequence
MASTEGANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKREK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp450180SLC1A2solute carrier family 1 member 29598VGNC:7755OMA, EggNOG
Macaque574358SLC1A2solute carrier family 1 member 29544Inparanoid, OMA, EggNOG
Mouse20511Slc1a2solute carrier family 1 (glial high affinity glutamate transporter), member 210090MGI:101931Inparanoid, OMA, EggNOG
Dog403750SLC1A2solute carrier family 1 member 29615VGNC:46262Inparanoid, OMA, EggNOG
Horse100067133SLC1A2solute carrier family 1 member 29796VGNC:23061Inparanoid, OMA, EggNOG
Cow541119SLC1A2solute carrier family 1 member 29913VGNC:34712Inparanoid, OMA, EggNOG
Pig100627068SLC1A2solute carrier family 1 member 29823OMA, EggNOG
Opossum100009860SLC1A2solute carrier family 1 member 213616Inparanoid, OMA, EggNOG
Platypus100076652SLC1A2solute carrier family 1 member 29258Inparanoid, OMA
Anole lizard100563190slc1a2solute carrier family 1 member 228377Inparanoid, OMA, EggNOG
Xenopus100494868slc1a2solute carrier family 1 member 28364XB-GENE-1005169Inparanoid, OMA, EggNOG
Zebrafish335836slc1a2bsolute carrier family 1 (glial high affinity glutamate transporter), member 2b7955ZDB-GENE-030131-7779Inparanoid, OMA
C. elegans180641glt-1Excitatory amino acid transporter6239Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    cation transporter    /    Excitatory amino acid transporter 2
DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC1 family of amino acid transporters    /    Glutamate transporter subfamily    /    Excitatory amino acid transporter 2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source