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PTGIS
| Description | Prostacyclin synthase |
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Gene and Protein Information
| Gene ID | 5740 |
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| Uniprot Accession IDs | Q3MII8 Q9HAX2 Q9HAX3 Q9HAX4 |
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| Ensembl ID | ENSP00000244043 |
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| Symbol | CYP8 CYP8A1 CYP8 PGIS PTGI CYP8A1 |
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| Family | Belongs to the cytochrome P450 family. |
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| Sequence | MAWAALLGLLAALLLLLLLSRRRTRRPGEPPLDLGSIPWLGYALDFGKDAASFLTRMKEKHGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDEKARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAGSGWHEMGLLDFSYSFLLRAGYLTLYGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDHMCSVKSRLWKLLSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQLWATQGNMGPAAFWLLLFLLKNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRLTAAPFITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINADVEIPEFDLSRYGFGLMQPEHDVPVRYRIRP Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 458323 | PTGIS | prostaglandin I2 synthase | 9598 | VGNC:14478 | OMA, EggNOG |
| Macaque | 703407 | PTGIS | prostaglandin I2 synthase | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 19223 | Ptgis | prostaglandin I2 (prostacyclin) synthase | 10090 | MGI:1097156 | Inparanoid, OMA, EggNOG |
| Rat | | AABR07054614.1 | - | 10116 | | OMA, EggNOG |
| Dog | 100856661 | PTGIS | prostaglandin I2 synthase | 9615 | VGNC:45149 | Inparanoid, OMA, EggNOG |
| Horse | 100071412 | PTGIS | prostaglandin I2 synthase | 9796 | VGNC:21995 | Inparanoid, OMA, EggNOG |
| Cow | 282021 | PTGIS | prostaglandin I2 synthase | 9913 | VGNC:33509 | Inparanoid, OMA, EggNOG |
| Pig | 100126284 | PTGIS | prostaglandin I2 synthase | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100029131 | PTGIS | prostaglandin I2 synthase | 13616 | | Inparanoid, EggNOG |
| Platypus | | PTGIS | prostaglandin I2 synthase [Source:HGNC Symbol;Acc:HGNC:9603] | 9258 | | OMA, EggNOG |
| Anole lizard | 100565699 | ptgis | prostaglandin I2 synthase | 28377 | | Inparanoid, OMA |
| Xenopus | 100492372 | ptgis | prostaglandin I2 (prostacyclin) synthase | 8364 | XB-GENE-487693 | Inparanoid, OMA |
| Zebrafish | 559148 | ptgis | prostaglandin I2 (prostacyclin) synthase | 7955 | ZDB-GENE-070116-1 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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