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PTPN11
| Description | Tyrosine-protein phosphatase non-receptor type 11 |
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Gene and Protein Information
| Gene ID | 5781 |
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| Uniprot Accession IDs | A8K1D9 Q96HD7 |
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| Ensembl ID | ENSP00000340944 |
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| Symbol | PTP2C SHPTP2 CFC NS1 JMML SHP2 BPTP3 PTP2C METCDS PTP-1D SH-PTP2 SH-PTP3 |
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| Family | Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily. |
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| Sequence | MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 104001066 | PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 9598 | VGNC:5553 | OMA, EggNOG |
| Macaque | 712044 | PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 19247 | Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 10090 | MGI:99511 | Inparanoid, OMA, EggNOG |
| Rat | 25622 | Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 10116 | RGD:3447 | Inparanoid, OMA, EggNOG |
| Dog | 477488 | PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 9615 | VGNC:45168 | Inparanoid, OMA, EggNOG |
| Horse | 100056857 | PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 9796 | VGNC:22011 | Inparanoid, OMA, EggNOG |
| Cow | 533590 | PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 9913 | VGNC:33530 | Inparanoid, OMA, EggNOG |
| Pig | 100170851 | PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100028991 | PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 13616 | | Inparanoid, OMA, EggNOG |
| Chicken | 395815 | PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 9031 | CGNC:49495 | Inparanoid, OMA |
| Anole lizard | 100559345 | ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 28377 | | Inparanoid, OMA |
| Zebrafish | 333979 | ptpn11a | protein tyrosine phosphatase, non-receptor type 11, a | 7955 | ZDB-GENE-030131-5911 | Inparanoid, OMA |
| Fruitfly | 45278 | csw | corkscrew | 7227 | FBgn0000382 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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