PTPRF

DescriptionReceptor-type tyrosine-protein phosphatase F

Gene and Protein Information

Gene ID5792
Uniprot Accession IDs D3DPX6 D3DPX7 Q5T021 Q5T022 Q5W9G2 Q86WS0
Ensembl ID ENSP00000353030
Symbol LAR LAR BNAH2
FamilyBelongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
Sequence
MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp456828PTPRFprotein tyrosine phosphatase, receptor type F9598VGNC:9889OMA, EggNOG
Macaque701160PTPRFprotein tyrosine phosphatase, receptor type F9544OMA, EggNOG
Mouse19268Ptprfprotein tyrosine phosphatase, receptor type, F10090MGI:102695Inparanoid, OMA
Rat360406Ptprfprotein tyrosine phosphatase, receptor type, F10116RGD:3453Inparanoid, OMA
Dog475389PTPRFprotein tyrosine phosphatase, receptor type F9615VGNC:45187Inparanoid, OMA
Horse100053205PTPRFprotein tyrosine phosphatase, receptor type F9796VGNC:49527Inparanoid, OMA
Cow512072PTPRFprotein tyrosine phosphatase, receptor type F9913VGNC:33550Inparanoid, OMA
Chicken424568PTPRFprotein tyrosine phosphatase, receptor type F9031CGNC:52218Inparanoid, OMA
Anole lizard100566297ptprfprotein tyrosine phosphatase, receptor type F28377Inparanoid, OMA
Xenopus100493254ptprfprotein tyrosine phosphatase, receptor type F8364XB-GENE-495325Inparanoid, OMA
Zebrafish140819ptprfaprotein tyrosine phosphatase, receptor type, f, a7955ZDB-GENE-020107-2Inparanoid, OMA
C. elegans174685ptp-3Protein-tyrosine-phosphatase6239Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    protein phosphatase    /    Receptor-type tyrosine-protein phosphatase F
protein    /    receptor    /    Receptor-type tyrosine-protein phosphatase F
protein    /    phosphatase    /    Receptor-type tyrosine-protein phosphatase F
protein    /    hydrolase    /    Receptor-type tyrosine-protein phosphatase F
DTO Classes
protein    /    Enzyme    /    Hydrolase    /    Phosphatase    /    Protein phosphatase    /    Receptor-type tyrosine-protein phosphatase F

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source