RAF1

DescriptionRAF proto-oncogene serine/threonine-protein kinase

Gene and Protein Information

Gene ID5894
Uniprot Accession IDs B0LPH8 B2R5N3 Q15278 Q9UC20
Ensembl ID ENSP00000251849
Symbol RAF NS5 CRAF Raf-1 c-Raf CMD1NN
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Sequence
MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp460182RAF1Raf-1 proto-oncogene, serine/threonine kinase9598VGNC:12161OMA, EggNOG
Macaque694725RAF1Raf-1 proto-oncogene, serine/threonine kinase9544Inparanoid, OMA, EggNOG
Mouse110157Raf1v-raf-leukemia viral oncogene 110090MGI:97847Inparanoid, OMA, EggNOG
Rat24703Raf1Raf-1 proto-oncogene, serine/threonine kinase10116RGD:3531Inparanoid, OMA
Dog484648RAF1Raf-1 proto-oncogene, serine/threonine kinase9615VGNC:45325Inparanoid, OMA
Horse100051110RAF1Raf-1 proto-oncogene, serine/threonine kinase9796Inparanoid, OMA
Opossum100015410RAF1Raf-1 proto-oncogene, serine/threonine kinase13616Inparanoid, OMA
Chicken396245RAF1Raf-1 proto-oncogene, serine/threonine kinase9031CGNC:3714Inparanoid, OMA
Anole lizard100557613raf1Raf-1 proto-oncogene, serine/threonine kinase28377Inparanoid, OMA
Zebrafish557109raf1bRaf-1 proto-oncogene, serine/threonine kinase b7955ZDB-GENE-090826-2Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    RAF family    /    Raf proto-oncogene serine/threonine-protein kinase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source