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Protein or Target Summary

RAF proto-oncogene serine/threonine-protein kinase

Gene ID5894
uniprotP04049
Gene NameRAF1
Ensernbl IDENSP00000251849
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Sequence
MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN5894RAF1RAF proto-oncogene serine/threonine-protein kinaseP04049
MOUSERaf1RAF proto-oncogene serine/threonine-protein kinaseF6TUC4
MOUSERaf1Protein kinase raf 1Q99N73
MOUSERaf1CRAF proteinQ8VI85
MOUSERaf1Uncharacterized proteinQ9CU36
MOUSERaf1RAF proto-oncogene serine/threonine-protein kinaseA0A0N4SV36
MOUSERaf1RAF proto-oncogene serine/threonine-protein kinaseA0A0N4SWH5
MOUSE110157Raf1RAF proto-oncogene serine/threonine-protein kinaseQ99N57
RAT24703Raf1RAF proto-oncogene serine/threonine-protein kinaseP11345

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    RAF family    /    Raf proto-oncogene serine/threonine-protein kinase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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