RET

DescriptionProto-oncogene tyrosine-protein kinase receptor Ret

Gene and Protein Information

Gene ID5979
Uniprot Accession IDs A8K6Z2 Q15250 Q9BTB0 Q9H4A2
Ensembl ID ENSP00000347942
Symbol CDHF12 CDHR16 PTC RET51 PTC MTC1 HSCR1 MEN2A MEN2B CDHF12 CDHR16 RET-ELE1
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family.
Sequence
MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELVAVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYPNDSVYANWMLSPSAAKLMDTFDS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp100612888RETret proto-oncogene9598VGNC:12455OMA, EggNOG
Macaque703466RETret proto-oncogene9544OMA, EggNOG
Mouse19713Retret proto-oncogene10090MGI:97902Inparanoid, OMA, EggNOG
Rat24716Retret proto-oncogene10116RGD:3556Inparanoid, OMA, EggNOG
Dog403494RETret proto-oncogene9615VGNC:45481Inparanoid, OMA, EggNOG
Horse100146791RETret proto-oncogene9796VGNC:51660OMA, EggNOG
Cow515924RETret proto-oncogene9913VGNC:33876Inparanoid, OMA, EggNOG
Pig100155053RETret proto-oncogene9823OMA, EggNOG
Opossum100016023RETret proto-oncogene13616Inparanoid, EggNOG
Chicken396107RETret proto-oncogene9031CGNC:1837Inparanoid, OMA
Anole lizardRETret proto-oncogene [Source:HGNC Symbol;Acc:HGNC:9967]28377Inparanoid, OMA, EggNOG
Xenopus100495902retret proto-oncogene8364XB-GENE-485176Inparanoid, OMA, EggNOG
Zebrafish30512retret proto-oncogene receptor tyrosine kinase7955ZDB-GENE-980526-307Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    RET family    /    Proto-oncogene tyrosine-protein kinase receptor ret

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source