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RARG

DescriptionRetinoic acid receptor gamma

Gene and Protein Information

Gene ID5916
Uniprot Accession IDs P13631 B7Z492 B7Z4F1 B7ZAE4 J3KNP6 P22932 Q15281 Q52LZ8 Q9BYX8 Q9H1I3 Q9UJ38 RAR-gamma
Ensembl ID ENSP00000388510
Symbol NR1B3 RARC NR1B3
FamilyBelongs to the nuclear hormone receptor family. NR1 subfamily.
Sequence
MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp451935RARGretinoic acid receptor gamma9598VGNC:8514OMA, EggNOG
Macaque699532RARGretinoic acid receptor gamma9544Inparanoid, OMA, EggNOG
Mouse19411Rargretinoic acid receptor, gamma10090MGI:97858Inparanoid, OMA, EggNOG
Rat685072Rargretinoic acid receptor, gamma10116RGD:1583230Inparanoid, OMA
Dog486508RARGretinoic acid receptor gamma9615VGNC:45353Inparanoid, OMA
Horse100062026RARGretinoic acid receptor gamma9796VGNC:22186Inparanoid, OMA
Cow540425RARGretinoic acid receptor gamma9913VGNC:33730Inparanoid, OMA
Pig100626982RARGretinoic acid receptor gamma9823Inparanoid, OMA
Anole lizard100555055rargretinoic acid receptor gamma28377Inparanoid, OMA
Xenopus100485387rargretinoic acid receptor gamma8364XB-GENE-484127Inparanoid, OMA
Zebrafish100034753rargbretinoic acid receptor, gamma b7955ZDB-GENE-070314-1Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transcription factor    /    Retinoic acid receptor gamma
protein    /    receptor    /    Retinoic acid receptor gamma
protein    /    nucleic acid binding    /    Retinoic acid receptor gamma
protein    /    C4 zinc finger nuclear receptor    /    Retinoic acid receptor gamma
DTO Classes
protein    /    Nuclear receptor    /    Retinoic acid receptors    /    Retinoic acid receptor gamma

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

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      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      1.Nagpal, S S and 6 more authors. 1999-08-06 Retinoid-dependent recruitment of a histone H1 displacement activity by retinoic acid receptor. [PMID:10428834]
      2.Boudjelal, Mohamed M, Voorhees, John J JJ and Fisher, Gary J GJ. 2002-03-10 Retinoid signaling is attenuated by proteasome-mediated degradation of retinoid receptors in human keratinocyte HaCaT cells. [PMID:11855864]
      3.Pettersson, F F, Dalgleish, A G AG, Bissonnette, R P RP and Colston, K W KW. 2002-08-27 Retinoids cause apoptosis in pancreatic cancer cells via activation of RAR-gamma and altered expression of Bcl-2/Bax. [PMID:12189556]
      4.Klaholz, Bruno B and Moras, Dino D. 2002-09 C-H...O hydrogen bonds in the nuclear receptor RARgamma--a potential tool for drug selectivity. [PMID:12220491]
      5.Richter, Frank F and 7 more authors.Immunohistochemical localization of the retinoic Acid receptors in human prostate. [PMID:12399530]
      6.Strausberg, Robert L RL and 83 more authors. 2002-12-24 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. [PMID:12477932]
      7.Hauksdottir, Herborg H, Farboud, Behnom B and Privalsky, Martin L ML. 2003-03 Retinoic acid receptors beta and gamma do not repress, but instead activate target gene transcription in both the absence and presence of hormone ligand. [PMID:12554770]
      8.Farboud, Behnom B, Hauksdottir, Herborg H, Wu, Yun Y and Privalsky, Martin L ML. 2003-04 Isotype-restricted corepressor recruitment: a constitutively closed helix 12 conformation in retinoic acid receptors beta and gamma interferes with corepressor recruitment and prevents transcriptional repression. [PMID:12665583]
      9.Leid, M M and 9 more authors. 1992-01-24 Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. [PMID:1310259]
      10.Vollberg, T M TM and 5 more authors. 1992-05 Retinoic acid receptors as regulators of human epidermal keratinocyte differentiation. [PMID:1318502]