SERPINE1

DescriptionPlasminogen activator inhibitor 1

Gene and Protein Information

Gene ID5054
Uniprot Accession IDs B7Z4S0 F8WD53 PAI
Ensembl ID ENSP00000223095
Symbol PAI1 PLANH1 PAI PAI1 PAI-1 PLANH1
FamilyBelongs to the serpin family.
Sequence
MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp472467SERPINE1serpin family E member 19598VGNC:10053OMA, EggNOG
Macaque713883SERPINE1serpin family E member 19544Inparanoid, OMA, EggNOG
Mouse18787Serpine1serine (or cysteine) peptidase inhibitor, clade E, member 110090MGI:97608Inparanoid, OMA, EggNOG
Rat24617Serpine1serpin family E member 110116RGD:3249Inparanoid, OMA, EggNOG
Dog403476SERPINE1serpin family E member 19615VGNC:46036Inparanoid, OMA, EggNOG
Horse100033931SERPINE1serpin family E member 19796VGNC:22856Inparanoid, OMA, EggNOG
Cow281375SERPINE1serpin family E member 19913VGNC:34476Inparanoid, OMA, EggNOG
Pig396945SERPINE1serpin family E member 19823Inparanoid, OMA, EggNOG
Opossum100017921SERPINE1serpin family E member 113616Inparanoid, OMA, EggNOG
Anole lizard100558317serpine1serpin family E member 128377Inparanoid, OMA, EggNOG
Xenopus100127732serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 18364XB-GENE-969639Inparanoid, OMA, EggNOG
Zebrafish100136840serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 17955ZDB-GENE-070912-60Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    enzyme modulator    /    serine protease inhibitor    /    Plasminogen activator inhibitor 1
DTO Classes
protein    /    Enzyme modulator    /    Protease inhibitor    /    Serine protease inhibitor    /    Plasminogen activator inhibitor 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source