PPM1A

DescriptionProtein phosphatase 1A

Gene and Protein Information

Gene ID5494
Uniprot Accession IDs B5BU11 J3KNM0 O75551
Ensembl ID ENSP00000327255
Symbol PPPM1A PP2CA PP2Calpha PP2C-ALPHA
FamilyBelongs to the PP2C family.
Sequence
MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSTSTDDMW
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452950PPM1Aprotein phosphatase, Mg2+/Mn2+ dependent 1A9598VGNC:8292OMA, EggNOG
Macaque702987PPM1Aprotein phosphatase, Mg2+/Mn2+ dependent 1A9544Inparanoid, OMA, EggNOG
Mouse19042Ppm1aprotein phosphatase 1A, magnesium dependent, alpha isoform10090MGI:99878Inparanoid, OMA, EggNOG
Rat24666Ppm1aprotein phosphatase, Mg2+/Mn2+ dependent, 1A10116RGD:3373Inparanoid, OMA, EggNOG
Dog480344PPM1Aprotein phosphatase, Mg2+/Mn2+ dependent 1A9615VGNC:44862Inparanoid, OMA, EggNOG
Horse100051348PPM1Aprotein phosphatase, Mg2+/Mn2+ dependent 1A9796VGNC:21740Inparanoid, OMA, EggNOG
Cow281994PPM1Aprotein phosphatase, Mg2+/Mn2+ dependent 1A9913Inparanoid, OMA, EggNOG
Pig100738389PPM1Aprotein phosphatase, Mg2+/Mn2+ dependent 1A9823OMA, EggNOG
Opossum100021641PPM1Aprotein phosphatase, Mg2+/Mn2+ dependent 1A13616Inparanoid, EggNOG
Platypus100086309PPM1Aprotein phosphatase, Mg2+/Mn2+ dependent 1A9258Inparanoid, OMA, EggNOG
Chicken423525PPM1Aprotein phosphatase, Mg2+/Mn2+ dependent 1A9031CGNC:9036Inparanoid, OMA, EggNOG
Anole lizard100558424ppm1aprotein phosphatase, Mg2+/Mn2+ dependent 1A28377Inparanoid, OMA, EggNOG
Xenopus548912ppm1aprotein phosphatase, Mg2+/Mn2+ dependent 1A8364XB-GENE-852654Inparanoid, OMA, EggNOG
Zebrafish30704ppm1aaprotein phosphatase, Mg2+/Mn2+ dependent, 1Aa7955ZDB-GENE-991102-15Inparanoid, OMA
C. elegans179469ppm-1Protein phosphatase ppm-16239Inparanoid, OMA
Fruitfly43481alphalphabet7227FBgn0086361Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    enzyme modulator    /    kinase inhibitor    /    Protein phosphatase 1A
protein    /    enzyme modulator    /    protein phosphatase    /    Protein phosphatase 1A
protein    /    enzyme modulator    /    phosphatase    /    Protein phosphatase 1A
protein    /    enzyme modulator    /    hydrolase    /    Protein phosphatase 1A
DTO Classes
protein    /    Enzyme    /    Hydrolase    /    Phosphatase    /    Protein phosphatase    /    Protein phosphatase 1A

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source