PLCG1

Description1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Gene and Protein Information

Gene ID5335
Uniprot Accession IDs B7ZLY7 B9EGH4 E1P5W4 Q2V575
Ensembl ID ENSP00000244007
Symbol PLC1 PLC1 NCKAP3 PLC-II PLC148 PLCgamma1
Sequence
MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp458253PLCG1phospholipase C gamma 19598VGNC:6244OMA, EggNOG
Macaque697069PLCG1phospholipase C gamma 19544Inparanoid, OMA, EggNOG
Mouse18803Plcg1phospholipase C, gamma 110090MGI:97615Inparanoid, OMA, EggNOG
Rat25738Plcg1phospholipase C, gamma 110116RGD:3347Inparanoid, OMA
Dog485874PLCG1phospholipase C gamma 19615VGNC:44651Inparanoid, OMA, EggNOG
Horse100070545PLCG1phospholipase C gamma 19796VGNC:21542Inparanoid, OMA, EggNOG
Cow281987PLCG1phospholipase C gamma 19913VGNC:32988Inparanoid, OMA, EggNOG
Pig100152497PLCG1phospholipase C gamma 19823OMA, EggNOG
Opossum100032696PLCG1phospholipase C gamma 113616Inparanoid, EggNOG
Chicken419175PLCG1phospholipase C gamma 19031CGNC:50935Inparanoid, OMA, EggNOG
Anole lizard100559347plcg1phospholipase C gamma 128377Inparanoid, OMA, EggNOG
Xenopus100496674plcg1phospholipase C gamma 18364XB-GENE-982496Inparanoid, OMA, EggNOG
Zebrafish373867plcg1phospholipase C, gamma 17955ZDB-GENE-030421-3Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    G-protein modulator    /    phospholipase    /    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
protein    /    G-protein modulator    /    guanyl-nucleotide exchange factor    /    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
protein    /    G-protein modulator    /    signaling molecule    /    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
protein    /    G-protein modulator    /    calcium-binding protein    /    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
DTO Classes
protein    /    Enzyme    /    Hydrolase    /    Lipase    /    Phospholipase    /    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source