PTPRB

DescriptionReceptor-type tyrosine-protein phosphatase beta

Gene and Protein Information

Gene ID5787
Uniprot Accession IDs B7ZKS8 B7ZKT0 C9JX87 F5H3G6 Q14D85 Q3MIV7 Protein-tyrosine phosphatase beta
Ensembl ID ENSP00000334928
Symbol PTPB PTPB HPTPB VEPTP HPTP-BETA R-PTP-BETA
FamilyBelongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.
Sequence
MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCDPTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPVYSRH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452074PTPRBprotein tyrosine phosphatase, receptor type B9598VGNC:52073OMA, EggNOG
Macaque718564PTPRBprotein tyrosine phosphatase, receptor type B9544Inparanoid, OMA, EggNOG
Mouse19263Ptprbprotein tyrosine phosphatase, receptor type, B10090MGI:97809Inparanoid, OMA, EggNOG
Rat314843Ptprbprotein tyrosine phosphatase, receptor type, B10116RGD:1305922Inparanoid, OMA
Dog481162PTPRBprotein tyrosine phosphatase, receptor type B9615VGNC:45183Inparanoid, OMA, EggNOG
Cow505696PTPRBprotein tyrosine phosphatase, receptor type B9913VGNC:33545OMA, EggNOG
Pig100156181PTPRBprotein tyrosine phosphatase, receptor type B9823OMA, EggNOG
Opossum100015898PTPRBprotein tyrosine phosphatase, receptor type B13616Inparanoid, OMA, EggNOG
PlatypusPTPRBprotein tyrosine phosphatase, receptor type B [Source:HGNC Symbol;Acc:HGNC:9665]9258OMA, EggNOG
Chicken417853PTPRBprotein tyrosine phosphatase, receptor type B9031CGNC:7640Inparanoid, OMA, EggNOG
Anole lizard100567589ptprbprotein tyrosine phosphatase, receptor type B28377OMA, EggNOG
Xenopusptprbprotein tyrosine phosphatase, receptor type B [Source:Xenbase;Acc:XB-GENE-991728]8364OMA, EggNOG
Zebrafish100149130ptprbprotein tyrosine phosphatase, receptor type, b7955ZDB-GENE-101108-3Inparanoid, OMA

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source