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Targets(Human)
PRTN3

PRTN3

Description	Myeloblastin

Gene and Protein Information

Gene ID	5657
Uniprot Accession IDs	P24158 P15637 P18078 Q4VB08 Q4VB09 Q6LBM7 Q6LBN2 Q9UD25 Q9UQD8
Ensembl ID	ENSP00000234347
Symbol	MBN MBN MBT NP4 P29 PR3 ACPA AGP7 NP-4 PR-3 CANCA C-ANCA
Family	Belongs to the peptidase S1 family. Elastase subfamily.
Sequence	MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	749895	PRTN3	proteinase 3	9598		Inparanoid, EggNOG
Mouse	19152	Prtn3	proteinase 3	10090	MGI:893580	Inparanoid, OMA, EggNOG
Rat	314615	Prtn3	proteinase 3	10116	RGD:1304898	Inparanoid, OMA, EggNOG
Horse		PRTN3	proteinase 3 [Source:HGNC Symbol;Acc:HGNC:9495]	9796		OMA, EggNOG
Cow	100298591	PRTN3	proteinase 3	9913	VGNC:33427	Inparanoid, OMA, EggNOG
Pig	106509464	PRTN3	proteinase 3	9823		OMA, EggNOG
Opossum	100030473	LOC100030473	myeloblastin	13616		OMA, EggNOG
Xenopus	448597	prtn3	proteinase 3	8364	XB-GENE-5805214	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Myeloblastin
protein    /    protease    /    Myeloblastin
protein    /    hydrolase    /    Myeloblastin

DTO Classes
protein / Enzyme / Protease / Serine protease / Myeloblastin

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

A total of 16 itemsPrev12 NextTopage

Name	Direct Associated Targets	Disease Type	Mondoid
Wegener Granulomatosis	5	Monarch	MONDO:0012105
osteosarcoma	7970	Expression Atlas	MONDO:0009807
Granulomatosis with Polyangiitis	5	CTD	MONDO:0012105
Leukemia, Myelogenous, Chronic, BCR-ABL Positive	28	CTD	MONDO:0011996
granulomatosis with polyangiitis	5	eRAM	MONDO:0012105
chronic myelocytic leukemia	28	eRAM	MONDO:0011996
Myeloid Leukemia, Chronic	28	DisGeNET	MONDO:0011996
Granulomatosis with polyangiitis	5	DisGeNET	MONDO:0012105
Primary biliary cholangitis	0	JensenLab Experiment TIGA
Vasculitis	0	JensenLab Text Mining

Bibliography

A total of 143 itemsPrev12 3 4 5…15 NextTopage

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