PTPN22

DescriptionTyrosine-protein phosphatase non-receptor type 22

Gene and Protein Information

Gene ID26191
Uniprot Accession IDs A0N0K6 B1ALC8 D4NZ71 E9PLD8 E9PPI1 O95063 O95064 Q6IPX8 Q8WVM1
Ensembl ID ENSP00000352833
Symbol PTPN8 LYP PEP LYP1 LYP2 PTPN8 PTPN22.5 PTPN22.6
FamilyBelongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.
Sequence
MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDKHSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSEISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQESAVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTSEPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIETYSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNSSSFLNFGFANRFSKPKGPRNPPPTWNI
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp457136PTPN22protein tyrosine phosphatase, non-receptor type 229598VGNC:9886OMA, EggNOG
Macaque707433PTPN22protein tyrosine phosphatase, non-receptor type 229544Inparanoid, OMA, EggNOG
Mouse19260Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)10090MGI:107170Inparanoid, OMA, EggNOG
Rat295338Ptpn22protein tyrosine phosphatase, non-receptor type 2210116RGD:1307992Inparanoid, OMA, EggNOG
Dog483124PTPN22protein tyrosine phosphatase, non-receptor type 229615VGNC:45175Inparanoid, OMA, EggNOG
Horse100059247PTPN22protein tyrosine phosphatase, non-receptor type 229796VGNC:22018Inparanoid, OMA, EggNOG
Cow518992PTPN22protein tyrosine phosphatase, non-receptor type 229913VGNC:33536OMA, EggNOG
Opossum100033164PTPN22protein tyrosine phosphatase, non-receptor type 2213616Inparanoid, OMA, EggNOG
Chicken772032PTPN22protein tyrosine phosphatase, non-receptor type 229031CGNC:14668Inparanoid, OMA
Anole lizardPTPN22protein tyrosine phosphatase, non-receptor type 22 [Source:HGNC Symbol;Acc:HGNC:9652]28377Inparanoid, OMA
Xenopus100495002ptpn22protein tyrosine phosphatase, non-receptor type 228364XB-GENE-853933Inparanoid, OMA

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

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