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RPS3

Description40S ribosomal protein S3

Gene and Protein Information

Gene ID6188
Uniprot Accession IDs P23396 B2R7N5 J3KN86 Q498B5 Q8NI95
Ensembl ID ENSP00000278572
Symbol S3
FamilyBelongs to the universal ribosomal protein uS3 family.
Sequence
MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPTGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPEPPAMPQPVPTA
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque695748RPS3ribosomal protein S39544Inparanoid, OMA, EggNOG
Mouse27050Rps3ribosomal protein S310090MGI:1350917Inparanoid, OMA, EggNOG
Rat140654Rps3ribosomal protein S310116RGD:619888Inparanoid, OMA
Dog476804RPS3ribosomal protein S39615VGNC:45736Inparanoid, OMA, EggNOG
Horse100051780RPS3ribosomal protein S39796OMA, EggNOG
Cow326588RPS3ribosomal protein S39913VGNC:34138Inparanoid, OMA, EggNOG
Pig733671RPS3ribosomal protein S39823Inparanoid, OMA, EggNOG
Opossum100010657RPS3ribosomal protein S313616Inparanoid, OMA, EggNOG
Chicken419069RPS3ribosomal protein S39031CGNC:13020Inparanoid, OMA, EggNOG
Anole lizard100567092rps3ribosomal protein S328377Inparanoid, OMA, EggNOG
Xenopus394724rps3ribosomal protein S38364XB-GENE-978298Inparanoid, OMA, EggNOG
Zebrafish336550rps3ribosomal protein S37955ZDB-GENE-030131-8494Inparanoid, OMA
C. elegans175879rps-340S ribosomal protein S36239Inparanoid, OMA
Fruitfly42761RpS3Ribosomal protein S37227FBgn0002622Inparanoid, EggNOG
S.cerevisiae855543RPS3ribosomal 40S subunit protein S34932S000005122Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    ribosomal protein    /    40S ribosomal protein S3
DTO Classes
protein    /    Nucleic acid binding    /    RNA binding protein    /    Ribosomal protein    /    40S ribosomal protein S3

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid
      atypical teratoid / rhabdoid tumor5491Expression AtlasMONDO:0020560
      diabetes mellitus1167Expression AtlasMONDO:0005015
      lung cancer4468Expression AtlasMONDO:0008903
      medulloblastoma, large-cell6269Expression AtlasMONDO:0002791
      multiple myeloma1334Expression AtlasMONDO:0009693
      Pick disease1910Expression AtlasMONDO:0008243
      sonic hedgehog group medulloblastoma7142Expression AtlasMONDO:0007959
      Waldenstrons macroglobulinemia770Expression AtlasMONDO:0000432
      Chromosomal Instability0CTD
      Melanoma246CTDMONDO:0005105

      Bibliography

      1.Yoshihama, Maki M and 10 more authors. 2002-03 The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. [PMID:11875025]
      2.Lee, Chang Hoon CH and 5 more authors. 2002-02-28 Electron paramagnetic resonance study reveals a putative iron-sulfur cluster in human rpS3 protein. [PMID:11911468]
      3.Lim, Yoon Y and 6 more authors. 2002-03-20 Complete genomic structure of human rpS3: identification of functional U15b snoRNA in the fifth intron. [PMID:11943484]
      4.Strausberg, Robert L RL and 83 more authors. 2002-12-24 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. [PMID:12477932]
      5.Sampath, Prabha P, Mazumder, Barsanjit B, Seshadri, Vasudevan V and Fox, Paul L PL. 2003-03 Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region. [PMID:12588972]
      6.Hegde, Vijay V, Wang, Mu M and Deutsch, Walter A WA. 2004-02-03 Characterization of human ribosomal protein S3 binding to 7,8-dihydro-8-oxoguanine and abasic sites by surface plasmon resonance. [PMID:14706345]
      7.Jang, Chang-Young CY, Lee, Jae Yung JY and Kim, Joon J. 2004-02-27 RpS3, a DNA repair endonuclease and ribosomal protein, is involved in apoptosis. [PMID:14988002]
      8.Meek, Sarah E M SE, Lane, William S WS and Piwnica-Worms, Helen H. 2004-07-30 Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins. [PMID:15161933]
      9.Kapp, Lee D LD and Lorsch, Jon R JR. 2004 The molecular mechanics of eukaryotic translation. [PMID:15189156]
      10.Beausoleil, Sean A SA and 8 more authors. 2004-08-17 Large-scale characterization of HeLa cell nuclear phosphoproteins. [PMID:15302935]