SAE1

DescriptionSUMO-activating enzyme subunit 1

Gene and Protein Information

Gene ID10055
Uniprot Accession IDs B2RDP5 B3KMQ2 F5GXX7 G3XAK6 O95717 Q9P020
Ensembl ID ENSP00000270225
Symbol AOS1 SUA1 UBLE1A AOS1 SUA1 UBLE1A HSPC140
FamilyBelongs to the ubiquitin-activating E1 family.
Sequence
MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp456159SAE1SUMO1 activating enzyme subunit 19598VGNC:2259OMA, EggNOG
Macaque717918SAE1SUMO1 activating enzyme subunit 19544Inparanoid, OMA, EggNOG
Mouse56459Sae1SUMO1 activating enzyme subunit 110090MGI:1929264Inparanoid, OMA, EggNOG
Rat308384Sae1SUMO1 activating enzyme subunit 110116RGD:1306098Inparanoid, OMA, EggNOG
Dog476425SAE1SUMO1 activating enzyme subunit 19615VGNC:45843Inparanoid, OMA, EggNOG
Horse100071215SAE1SUMO1 activating enzyme subunit 19796VGNC:22666Inparanoid, OMA, EggNOG
Cow505512SAE1SUMO1 activating enzyme subunit 19913VGNC:34261Inparanoid, OMA, EggNOG
Pig100515263SAE1SUMO1 activating enzyme subunit 19823OMA, EggNOG
Opossum100016572SAE1SUMO1 activating enzyme subunit 113616Inparanoid, OMA, EggNOG
Platypus100093563SAE1SUMO1 activating enzyme subunit 19258Inparanoid, OMA, EggNOG
Anole lizard100563027sae1SUMO1 activating enzyme subunit 128377Inparanoid, OMA, EggNOG
Xenopus549624sae1SUMO1 activating enzyme subunit 18364XB-GENE-923356Inparanoid, OMA, EggNOG
Zebrafish415148sae1SUMO1 activating enzyme subunit 17955ZDB-GENE-040625-21Inparanoid, OMA, EggNOG
C. elegans179409aos-1SUMO-activating enzyme subunit aos-16239Inparanoid, OMA
Fruitfly41532Aos1Activator of SUMO 17227FBgn0029512Inparanoid, EggNOG
S.cerevisiae856310AOS1E1 ubiquitin-activating protein AOS14932S000006384Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transfer/carrier protein    /    SUMO-activating enzyme subunit 1
protein    /    ligase    /    SUMO-activating enzyme subunit 1
DTO Classes
protein    /    Enzyme    /    Ligase    /    SUMO-activating enzyme subunit 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source