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| Description | Retinoic acid receptor RXR-gamma |
|---|
Gene and Protein Information
| Gene ID | 6258 |
|---|---|
| Uniprot Accession IDs | P48443 A6NIP1 Q6IBU7 |
| Ensembl ID | ENSP00000352900 |
| Symbol | NR2B3 RXRC NR2B3 |
| Family | Belongs to the nuclear hormone receptor family. NR2 subfamily. |
| Sequence | MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 457476 | RXRG | retinoid X receptor gamma | 9598 | VGNC:1534 | OMA, EggNOG |
| Macaque | 694807 | RXRG | retinoid X receptor gamma | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 20183 | Rxrg | retinoid X receptor gamma | 10090 | MGI:98216 | Inparanoid, OMA, EggNOG |
| Rat | 83574 | Rxrg | retinoid X receptor gamma | 10116 | RGD:620046 | Inparanoid, OMA, EggNOG |
| Dog | 478989 | RXRG | retinoid X receptor gamma | 9615 | VGNC:45819 | Inparanoid, OMA |
| Horse | 100060371 | RXRG | retinoid X receptor gamma | 9796 | VGNC:22641 | Inparanoid, OMA |
| Cow | 509500 | RXRG | retinoid X receptor gamma | 9913 | VGNC:34232 | Inparanoid, OMA |
| Pig | 445465 | RXRG | retinoid X receptor gamma | 9823 | Inparanoid, OMA | |
| Opossum | 100016615 | RXRG | retinoid X receptor gamma | 13616 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / transcription factor / Retinoic acid receptor rxr-gamma
protein / receptor / Retinoic acid receptor rxr-gamma
protein / nucleic acid binding / Retinoic acid receptor rxr-gamma
protein / C4 zinc finger nuclear receptor / Retinoic acid receptor rxr-gamma
protein / transcription factor / Retinoic acid receptor rxr-gamma
protein / receptor / Retinoic acid receptor rxr-gamma
protein / nucleic acid binding / Retinoic acid receptor rxr-gamma
protein / C4 zinc finger nuclear receptor / Retinoic acid receptor rxr-gamma
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
|---|
Bibliography
| 1.Ito, K K and 7 more authors. 2001-06 Retinoid receptors in the human endometrium and its disorders: a possible modulator of 17 beta-hydroxysteroid dehydrogenase. [PMID:11397877] |
| 2.Kim, S W SW and 7 more authors. 2001-10-04 Retinoid-dependent antagonism of serum response factor transactivation mediated by transcriptional coactivator proteins. [PMID:11641790] |
| 3.Brabender, Jan J and 10 more authors. 2002-02 The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer. [PMID:11839661] |
| 4.Wansa, K D Senali Abayratna KD, Harris, Jonathan M JM and Muscat, George E O GE. 2002-09-06 The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment. [PMID:12082103] |
| 5.Wang, Q Q, Fujii, H H and Knipp, G T GT.Expression of PPAR and RXR isoforms in the developing rat and human term placentas. [PMID:12361685] |
| 6.Kimura, Yuichiro Y and 9 more authors. 2002-12 Retinoid receptors in the developing human lung. [PMID:12444914] |
| 7.Strausberg, Robert L RL and 83 more authors. 2002-12-24 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. [PMID:12477932] |
| 8.Alfaro, Juan M JM and 5 more authors.Immunohistochemical detection of the retinoid X receptors alpha, beta, and gamma in human prostate. [PMID:12514092] |
| 9.Argmann, C A CA, Sawyez, C G CG, McNeil, C J CJ, Hegele, R A RA and Huff, M W MW. 2003-03-01 Activation of peroxisome proliferator-activated receptor gamma and retinoid X receptor results in net depletion of cellular cholesteryl esters in macrophages exposed to oxidized lipoproteins. [PMID:12615696] |
| 10.Leid, M M and 9 more authors. 1992-01-24 Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. [PMID:1310259] |