Protein or Target Summary
Rho-associated protein kinase 2
| Gene ID | 9475 |
|---|---|
| uniprot | O75116 |
| Gene Name | ROCK2 |
| Ensernbl ID | ENSP00000317985 |
| Family | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. |
| Sequence | MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPNKPS Show more |
Gene and Protein Information
| Species | Gene ID | Gene Symbol | Gene Name | Uniprot |
|---|---|---|---|---|
| HUMAN | 9475 | ROCK2 | Rho-associated protein kinase 2 | O75116 |
| MOUSE | 19878 | Rock2 | Rho-associated protein kinase 2 | P70336 |
| MOUSE | Rock2 | Rho-associated protein kinase 2 | A0A1Y7VLD1 | |
| MOUSE | 19878 | Rock2 | Rho-associated protein kinase | F8VPK5 |
| MOUSE | Rock2 | Uncharacterized protein | Q3UMT5 | |
| MOUSE | 19878 | Rock2 | Uncharacterized protein | Q3TR46 |
| MOUSE | Rock2 | Rho-associated protein kinase 2 | A0A1Y7VMN0 | |
| MOUSE | Rock2 | Uncharacterized protein | Q8CC95 | |
| MOUSE | Rock2 | MKIAA0619 protein | Q6A035 | |
| MOUSE | Rock2 | Uncharacterized protein | Q3UEZ9 | |
| RAT | 25537 | Rock2 | Rho-associated protein kinase 2 | Q62868 |
| RAT | 25537 | Rock2 | Rho-associated protein kinase | A0A0G2K5N6 |
| RAT | Rock2 | Rho-associated protein kinase | F1LQT3 |
Protein Classes
PANTHER Classes
protein / non-receptor serine/threonine protein kinase / Rho-associated protein kinase 2
protein / protein kinase / Rho-associated protein kinase 2
protein / transferase / Rho-associated protein kinase 2
protein / kinase / Rho-associated protein kinase 2
protein / non-receptor serine/threonine protein kinase / Rho-associated protein kinase 2
protein / protein kinase / Rho-associated protein kinase 2
protein / transferase / Rho-associated protein kinase 2
protein / kinase / Rho-associated protein kinase 2
DTO Classes
protein / Kinase / Protein kinase / AGC group / DMPK family / ROCK subfamily / Rho-associated protein kinase 2
protein / Kinase / Protein kinase / AGC group / DMPK family / ROCK subfamily / Rho-associated protein kinase 2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|
Source: DataSourcesLicenses.xlsx