| Description | Rho-associated protein kinase 2 |
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Gene and Protein Information
| Gene ID | 9475 |
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| Uniprot Accession IDs | Q53QZ0 Q53SJ7 Q9UQN5 |
| Ensembl ID | ENSP00000317985 |
| Symbol | KIAA0619 ROCK-II |
| Family | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. |
| Sequence | MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPNKPS Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 470307 | ROCK2 | Rho associated coiled-coil containing protein kinase 2 | 9598 | VGNC:6655 | OMA, EggNOG |
| Macaque | 708444 | ROCK2 | Rho associated coiled-coil containing protein kinase 2 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 19878 | Rock2 | Rho-associated coiled-coil containing protein kinase 2 | 10090 | MGI:107926 | Inparanoid, OMA, EggNOG |
| Rat | 25537 | Rock2 | Rho-associated coiled-coil containing protein kinase 2 | 10116 | RGD:3590 | Inparanoid, OMA, EggNOG |
| Dog | 482970 | ROCK2 | Rho associated coiled-coil containing protein kinase 2 | 9615 | VGNC:49640 | Inparanoid, OMA, EggNOG |
| Horse | 100072339 | ROCK2 | Rho associated coiled-coil containing protein kinase 2 | 9796 | VGNC:22497 | Inparanoid, OMA, EggNOG |
| Cow | 282041 | ROCK2 | Rho associated coiled-coil containing protein kinase 2 | 9913 | VGNC:34082 | Inparanoid, OMA, EggNOG |
| Pig | 397445 | ROCK2 | Rho associated coiled-coil containing protein kinase 2 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100032706 | ROCK2 | Rho associated coiled-coil containing protein kinase 2 | 13616 | Inparanoid, EggNOG | |
| Anole lizard | 100562729 | rock2 | Rho associated coiled-coil containing protein kinase 2 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100493965 | rock2 | Rho-associated, coiled-coil containing protein kinase 2 | 8364 | XB-GENE-959451 | Inparanoid, OMA |
| Zebrafish | 317747 | rock2a | rho-associated, coiled-coil containing protein kinase 2a | 7955 | ZDB-GENE-030115-3 | Inparanoid, OMA, EggNOG |
| C. elegans | 172088 | let-502 | Rho-associated protein kinase let-502 | 6239 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / non-receptor serine/threonine protein kinase / Rho-associated protein kinase 2
protein / protein kinase / Rho-associated protein kinase 2
protein / transferase / Rho-associated protein kinase 2
protein / kinase / Rho-associated protein kinase 2
protein / non-receptor serine/threonine protein kinase / Rho-associated protein kinase 2
protein / protein kinase / Rho-associated protein kinase 2
protein / transferase / Rho-associated protein kinase 2
protein / kinase / Rho-associated protein kinase 2
DTO Classes
protein / Kinase / Protein kinase / AGC group / DMPK family / ROCK subfamily / Rho-associated protein kinase 2
protein / Kinase / Protein kinase / AGC group / DMPK family / ROCK subfamily / Rho-associated protein kinase 2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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