DROSHA

Description	Ribonuclease 3

Gene and Protein Information

Gene ID	29102
Uniprot Accession IDs	E7EMP9 Q7Z5V2 Q86YH0 Q9NW73 Q9Y2V9 Q9Y4Y0
Ensembl ID	ENSP00000425979
Symbol	RN3 RNASE3L RNASEN RN3 ETOHI2 RNASEN RANSE3L RNASE3L HSA242976
Family	Belongs to the ribonuclease III family.
Sequence	MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	471576	DROSHA	drosha ribonuclease III	9598	VGNC:6858	OMA, EggNOG
Macaque	692081	DROSHA	drosha ribonuclease III	9544		Inparanoid, OMA, EggNOG
Mouse	14000	Drosha	drosha, ribonuclease type III	10090	MGI:1261425	Inparanoid, OMA, EggNOG
Rat	310159	Drosha	drosha ribonuclease III	10116	RGD:1307626	Inparanoid, OMA
Horse	100054238	DROSHA	drosha ribonuclease III	9796	VGNC:17318	Inparanoid, OMA, EggNOG
Cow	540168	DROSHA	drosha ribonuclease III	9913	VGNC:28211	Inparanoid, OMA, EggNOG
Pig	100524961	DROSHA	drosha ribonuclease III	9823		OMA, EggNOG
Opossum	100024147	DROSHA	drosha ribonuclease III	13616		Inparanoid, OMA, EggNOG
Chicken	420911	DROSHA	drosha ribonuclease III	9031	CGNC:9781	Inparanoid, OMA, EggNOG
Anole lizard	100557447	drosha	drosha ribonuclease III	28377		Inparanoid, OMA, EggNOG
Xenopus	100135003	drosha	drosha ribonuclease type III	8364	XB-GENE-494685	Inparanoid, OMA, EggNOG
Zebrafish	567505	rnasen	ribonuclease type III, nuclear	7955	ZDB-GENE-070209-23	Inparanoid, OMA, EggNOG
C. elegans	172830	drsh-1	Ribonuclease 3	6239		Inparanoid, EggNOG
Fruitfly	35747	drosha	CG8730 gene product from transcript CG8730-RA	7227	FBgn0026722	Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    endoribonuclease    /    Ribonuclease 3
protein    /    nucleic acid binding    /    RNA binding protein    /    Ribonuclease 3
protein    /    nucleic acid binding    /    nuclease    /    Ribonuclease 3

DTO Classes
protein / Enzyme / Nuclease / Endoribonuclease / Ribonuclease 3

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source