SLC12A1

DescriptionSolute carrier family 12 member 1

Gene and Protein Information

Gene ID6557
Uniprot Accession IDs A8JYA2 E9PDW4
Ensembl ID ENSP00000379822
Symbol NKCC2 BSC1 NKCC2
FamilyBelongs to the SLC12A transporter family.
Sequence
MSLNNSSNVFLDSVPSNTNRFQVSVINENHESSAAADDNTDPPHYEETSFGDEAQKRLRISFRPGNQECYDNFLQSGETAKTDASFHAYDSHTNTYYLQTFGHNTMDAVPKIEYYRNTGSISGPKVNRPSLLEIHEQLAKNVAVTPSSADRVANGDGIPGDEQAENKEDDQAGVVKFGWVKGVLVRCMLNIWGVMLFIRLSWIVGEAGIGLGVLIILLSTMVTSITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVDLLKESDSMMVDPTNDIRIIGSITVVILLGISVAGMEWEAKAQVILLVILLIAIANFFIGTVIPSNNEKKSRGFFNYQASIFAENFGPRFTKGEGFFSVFAIFFPAATGILAGANISGDLEDPQDAIPRGTMLAIFITTVAYLGVAICVGACVVRDATGNMNDTIISGMNCNGSAACGLGYDFSRCRHEPCQYGLMNNFQVMSMVSGFGPLITAGIFSATLSSALASLVSAPKVFQALCKDNIYKALQFFAKGYGKNNEPLRGYILTFLIAMAFILIAELNTIAPIISNFFLASYALINFSCFHASYAKSPGWRPAYGIYNMWVSLFGAVLCCAVMFVINWWAAVITYVIEFFLYVYVTCKKPDVNWGSSTQALSYVSALDNALELTTVEDHVKNFRPQCIVLTGGPMTRPALLDITHAFTKNSGLCICCEVFVGPRKLCVKEMNSGMAKKQAWLIKNKIKAFYAAVAADCFRDGVRSLLQASGLGRMKPNTLVIGYKKNWRKAPLTEIENYVGIIHDAFDFEIGVVIVRISQGFDISQVLQVQEELERLEQERLALEATIKDNECEEESGGIRGLFKKAGKLNITKTTPKKDGSINTSQSMHVGEFNQKLVEASTQFKKKQEKGTIDVWWLFDDGGLTLLIPYILTLRKKWKDCKLRIYVGGKINRIEEEKIVMASLLSKFRIKFADIHIIGDINIRPNKESWKVFEEMIEPYRLHESCKDLTTAEKLKRETPWKITDAELEAVKEKSYRQVRLNELLQEHSRAANLIVLSLPVARKGSISDLLYMAWLEILTKNLPPVLLVRGNHKNVLTFYS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp453410SLC12A1solute carrier family 12 member 19598VGNC:7779Inparanoid, OMA, EggNOG
Macaque714289SLC12A1solute carrier family 12 member 19544Inparanoid, OMA, EggNOG
Mouse20495Slc12a1solute carrier family 12, member 110090MGI:103150Inparanoid, OMA, EggNOG
Rat25065Slc12a1solute carrier family 12 member 110116RGD:3685Inparanoid, OMA, EggNOG
Dog478292SLC12A1solute carrier family 12 member 19615VGNC:46218Inparanoid, OMA, EggNOG
Horse100055787SLC12A1solute carrier family 12 member 19796VGNC:23019Inparanoid, OMA, EggNOG
Cow407161SLC12A1solute carrier family 12 member 19913VGNC:34664OMA, EggNOG
Pig100154291SLC12A1solute carrier family 12 member 19823OMA, EggNOG
Opossum100025723SLC12A1solute carrier family 12 member 113616Inparanoid, EggNOG
Chicken415433SLC12A1solute carrier family 12 member 19031CGNC:3673Inparanoid, OMA
Zebrafish100329975slc12a1solute carrier family 12 (sodium/potassium/chloride transporter), member 17955ZDB-GENE-080130-3Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC12 family of cation-coupled chloride transporters    /    Solute carrier family 12 member 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source