ROCK1
| Description | Rho-associated protein kinase 1 |
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Gene and Protein Information
| Gene ID | 6093 |
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| Uniprot Accession IDs | B0YJ91 Q2KHM4 Q59GZ4 |
| Ensembl ID | ENSP00000382697 |
| Symbol | ROCK-I P160ROCK |
| Family | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. |
| Sequence | MSTGDSFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLICPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 455326 | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | 9598 | VGNC:7330 | OMA, EggNOG |
| Macaque | 698223 | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 19877 | Rock1 | Rho-associated coiled-coil containing protein kinase 1 | 10090 | MGI:107927 | Inparanoid, OMA, EggNOG |
| Rat | 81762 | Rock1 | Rho-associated coiled-coil containing protein kinase 1 | 10116 | RGD:620424 | Inparanoid, OMA, EggNOG |
| Dog | 480181 | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | 9615 | VGNC:45688 | Inparanoid, OMA, EggNOG |
| Horse | 100034056 | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | 9796 | VGNC:22496 | Inparanoid, OMA, EggNOG |
| Cow | 785911 | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | 9913 | OMA, EggNOG | |
| Pig | 397447 | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100618269 | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | 13616 | Inparanoid, OMA | |
| Chicken | 373970 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 9031 | CGNC:11078 | Inparanoid, OMA |
| Anole lizard | 100558337 | rock1 | Rho associated coiled-coil containing protein kinase 1 | 28377 | Inparanoid, OMA | |
| Zebrafish | 100329779 | rock1 | Rho-associated, coiled-coil containing protein kinase 1 | 7955 | ZDB-GENE-100712-2 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / non-receptor serine/threonine protein kinase / Rho-associated protein kinase 1
protein / protein kinase / Rho-associated protein kinase 1
protein / transferase / Rho-associated protein kinase 1
protein / kinase / Rho-associated protein kinase 1
protein / non-receptor serine/threonine protein kinase / Rho-associated protein kinase 1
protein / protein kinase / Rho-associated protein kinase 1
protein / transferase / Rho-associated protein kinase 1
protein / kinase / Rho-associated protein kinase 1
DTO Classes
protein / Kinase / Protein kinase / AGC group / DMPK family / ROCK subfamily / Rho-associated protein kinase 1
protein / Kinase / Protein kinase / AGC group / DMPK family / ROCK subfamily / Rho-associated protein kinase 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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