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RAPGEF4
| Description | Rap guanine nucleotide exchange factor 4 |
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Gene and Protein Information
| Gene ID | 11069 |
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| Uniprot Accession IDs | B2R7R3 B7Z283 B7Z3T6 B7Z912 O95636 Q8IXK6 Q8TAA4 |
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| Ensembl ID | ENSP00000380271 |
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| Symbol | CGEF2 EPAC2 EPAC CGEF2 EPAC2 EPAC 2 Nbla00496 CAMP-GEFII |
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| Sequence | MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 459744 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 | 9598 | VGNC:2797 | OMA, EggNOG |
| Macaque | 698148 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 56508 | Rapgef4 | Rap guanine nucleotide exchange factor (GEF) 4 | 10090 | MGI:1917723 | Inparanoid, OMA, EggNOG |
| Dog | 488402 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 | 9615 | VGNC:53103 | Inparanoid, OMA, EggNOG |
| Horse | 100064121 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 | 9796 | VGNC:22182 | Inparanoid, OMA, EggNOG |
| Cow | 537312 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 | 9913 | VGNC:33725 | Inparanoid, OMA, EggNOG |
| Pig | 100511786 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 | 9823 | | OMA, EggNOG |
| Opossum | 100025283 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | 100084234 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 | 9258 | | Inparanoid, OMA, EggNOG |
| Anole lizard | 100567156 | rapgef4 | Rap guanine nucleotide exchange factor 4 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | | rapgef4 | Rap guanine nucleotide exchange factor 4 [Source:Xenbase;Acc:XB-GENE-6048644] | 8364 | | OMA, EggNOG |
| Zebrafish | 559170 | rapgef4 | Rap guanine nucleotide exchange factor (GEF) 4 | 7955 | ZDB-GENE-070912-385 | Inparanoid, OMA, EggNOG |
| C. elegans | 176432 | epac-1 | Rap guanine nucleotide exchange factor 1 | 6239 | | OMA, EggNOG |
| Fruitfly | 35588 | Epac | Exchange protein directly activated by cAMP | 7227 | FBgn0085421 | Inparanoid, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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