STAT3

DescriptionSignal transducer and activator of transcription 3

Gene and Protein Information

Gene ID6774
Uniprot Accession IDs A8K7B8 K7ENL3 O14916 Q9BW54
Ensembl ID ENSP00000264657
Symbol APRF APRF HIES ADMIO ADMIO1
FamilyBelongs to the transcription factor STAT family.
Sequence
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp454682STAT3signal transducer and activator of transcription 39598VGNC:9663OMA, EggNOG
Macaque574128STAT3signal transducer and activator of transcription 39544Inparanoid, OMA, EggNOG
Mouse20848Stat3signal transducer and activator of transcription 310090MGI:103038Inparanoid, OMA, EggNOG
Rat25125Stat3signal transducer and activator of transcription 310116RGD:3772Inparanoid, OMA, EggNOG
Dog490967STAT3signal transducer and activator of transcription 39615VGNC:46890Inparanoid, OMA, EggNOG
Horse100034011STAT3signal transducer and activator of transcription 39796VGNC:23665Inparanoid, OMA, EggNOG
Cow508541STAT3signal transducer and activator of transcription 39913VGNC:35371Inparanoid, OMA, EggNOG
Pig733648STAT3signal transducer and activator of transcription 39823Inparanoid, OMA, EggNOG
OpossumSTAT3signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364]13616Inparanoid, OMA, EggNOG
Chicken420027STAT3signal transducer and activator of transcription 39031CGNC:2374Inparanoid, OMA
Anole lizard100566559stat3signal transducer and activator of transcription 328377Inparanoid, OMA, EggNOG
Zebrafish30767stat3signal transducer and activator of transcription 3 (acute-phase response factor)7955ZDB-GENE-980526-68Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transcription factor    /    Signal transducer and activator of transcription 3
protein    /    nucleic acid binding    /    Signal transducer and activator of transcription 3
DTO Classes
protein    /    Nucleic acid binding    /    Signal transducer and activator of transcription 3

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source