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Protein or Target Summary

DNA (cytosine-5)-methyltransferase 3A

Gene ID1788
uniprotQ9Y6K1
Gene NameDNMT3A
Ensernbl IDENSP00000264709
FamilyBelongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Sequence
MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN1788DNMT3ADNA (cytosine-5)-methyltransferase 3AQ9Y6K1
MOUSE13435Dnmt3aDNA (cytosine-5)-methyltransferase 3AO88508
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UZG8
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UZH2
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UZK0
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UZU0
MOUSEDnmt3aUncharacterized proteinQ3TYD7
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UX63
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UY43
MOUSEDnmt3aUncharacterized proteinQ3UWR0
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UXY2
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UX07
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UZF8
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UZY8
MOUSEDnmt3aDNA (cytosine-5)-methyltransferase 3AG3UZN5
RAT444984Dnmt3aDNA (cytosine-5)-methyltransferase 3AQ1LZ53
RATDnmt3aDnmt3a proteinQ5FVL1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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