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TF

DescriptionSerotransferrin

Gene and Protein Information

Gene ID7018
Uniprot Accession IDs P02787 O43890 Q1HBA5 Q9NQB8 Q9UHV0 Transferrin
Ensembl ID ENSP00000385834
Symbol TFQTL1 PRO1557 PRO2086 HEL-S-71p
FamilyBelongs to the transferrin family.
Sequence
MRLAVGALLVCAVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAIAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYNKINHCRFDEFFSEGCAPGSKKDSSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSETKDLLFRDDTVCLAKLHDRNTYEKYLGEEYVKAVGNLRKCSTSSLLEACTFRRP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp460710TFtransferrin9598VGNC:12236Inparanoid, OMA, EggNOG
Macaque106992286LOC106992286serotransferrin9544OMA, EggNOG
MouseGm20425predicted gene 2042510090MGI:5141890Inparanoid, OMA
Rat24825Tftransferrin10116RGD:3845Inparanoid, OMA, EggNOG
Cow280705TFtransferrin9913Inparanoid, OMA
Xenopus613079tftransferrin8364XB-GENE-480506Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Serotransferrin
protein    /    transfer/carrier protein    /    Serotransferrin
protein    /    receptor    /    Serotransferrin
DTO Classes
protein    /    Enzyme    /    Protease    /    Serine protease    /    Serotransferrin

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      1.Bewley, M C MC and 9 more authors. 1999-02-23 X-ray crystallography and mass spectroscopy reveal that the N-lobe of human transferrin expressed in Pichia pastoris is folded correctly but is glycosylated on serine-32. [PMID:10029548]
      2.de Arriba Zerpa, G A GA and 7 more authors. 2000-08-15 Alternative splicing prevents transferrin secretion during differentiation of a human oligodendrocyte cell line. [PMID:10931525]
      3.West, A P AP and 5 more authors. 2000-12-08 Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE. [PMID:11027676]
      4.Beutler, E E and 5 more authors. 2000-12-15 Molecular characterization of a case of atransferrinemia. [PMID:11110675]
      5.Durrbach, A A, Raposo, G G, Tenza, D D, Louvard, D D and Coudrier, E E. 2000-05 Truncated brush border myosin I affects membrane traffic in polarized epithelial cells. [PMID:11208127]
      6.Weinzimer, S A SA and 5 more authors. 2001-04 Transferrin is an insulin-like growth factor-binding protein-3 binding protein. [PMID:11297622]
      7.Spitsyn, V A VA, Nafikova, A Kh AKh, Spitsyna, N Kh NKh and Afanas'eva, I S IS. 2001-05 [Genetic predisposition to development of toxic liver cirrhosis caused by alcohol]. [PMID:11436564]
      8.Kim, K W KW and 6 more authors. 2001-07-27 Transferrin C2 variant does not confer a risk for Alzheimer's disease in Koreans. [PMID:11445282]
      9.Kozyraki, R R and 8 more authors. 2001-10-23 Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia. [PMID:11606717]
      10.Douabin-Gicquel, V V and 10 more authors. 2001-10 Identification of 96 single nucleotide polymorphisms in eight genes involved in iron metabolism: efficiency of bioinformatic extraction compared with a systematic sequencing approach. [PMID:11702220]