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DNMT1
| Description | DNA (cytosine-5)-methyltransferase 1 |
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Gene and Protein Information
| Gene ID | 1786 |
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| Uniprot Accession IDs | A0AV63 B7ZLW6 Q9UHG5 Q9ULA2 Q9UMZ6 Dnmt1 |
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| Ensembl ID | ENSP00000352516 |
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| Symbol | AIM CXXC9 DNMT AIM DNMT MCMT CXXC9 HSN1E ADCADN m.HsaI |
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| Family | Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. |
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| Sequence | MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQACEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESASAKIKEEEAAKD Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 107969662 | DNMT1 | DNA methyltransferase 1 | 9598 | VGNC:10201 | OMA, EggNOG |
| Macaque | 574321 | DNMT1 | DNA methyltransferase 1 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 13433 | Dnmt1 | DNA methyltransferase (cytosine-5) 1 | 10090 | MGI:94912 | Inparanoid, OMA, EggNOG |
| Rat | 84350 | Dnmt1 | DNA methyltransferase 1 | 10116 | RGD:620979 | Inparanoid, OMA, EggNOG |
| Dog | 476715 | DNMT1 | DNA methyltransferase 1 | 9615 | | Inparanoid, EggNOG |
| Horse | 100058341 | DNMT1 | DNA methyltransferase 1 | 9796 | VGNC:17255 | Inparanoid, OMA, EggNOG |
| Cow | 281119 | DNMT1 | DNA methyltransferase 1 | 9913 | VGNC:28145 | Inparanoid, OMA, EggNOG |
| Pig | 606746 | DNMT1 | DNA methyltransferase 1 | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100013445 | LOC100013445 | DNA (cytosine-5)-methyltransferase 1-like | 13616 | | OMA, EggNOG |
| Anole lizard | 100565926 | dnmt1 | DNA methyltransferase 1 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100151716 | dnmt1 | DNA methyltransferase 1 | 8364 | XB-GENE-965562 | Inparanoid, OMA, EggNOG |
| Zebrafish | 30430 | dnmt1 | DNA (cytosine-5-)-methyltransferase 1 | 7955 | ZDB-GENE-990714-15 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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