CARS

DescriptionCysteine--tRNA ligase, cytoplasmic

Gene and Protein Information

Gene ID833
Uniprot Accession IDs Q53XI8 Q5HYE4 Q9HD24 Q9HD25
Ensembl ID ENSP00000369897
Symbol CARS1 CYSRS MGC:11246
FamilyBelongs to the class-I aminoacyl-tRNA synthetase family.
Sequence
MADSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp450962CARScysteinyl-tRNA synthetase9598VGNC:11276OMA, EggNOG
Macaque706502CARScysteinyl-tRNA synthetase9544Inparanoid, OMA, EggNOG
Mouse27267Carscysteinyl-tRNA synthetase10090MGI:1351477Inparanoid, OMA, EggNOG
Rat293638Carscysteinyl-tRNA synthetase10116RGD:1310747Inparanoid, OMA
Dog475998CARScysteinyl-tRNA synthetase9615VGNC:38726Inparanoid, OMA, EggNOG
Horse100060138CARScysteinyl-tRNA synthetase9796VGNC:16061Inparanoid, OMA, EggNOG
Cow515715CARScysteinyl-tRNA synthetase9913VGNC:26773Inparanoid, OMA, EggNOG
Pig100516312CARScysteinyl-tRNA synthetase9823OMA, EggNOG
Opossum100015261CARScysteinyl-tRNA synthetase13616Inparanoid, OMA, EggNOG
Chicken423086CARScysteinyl-tRNA synthetase9031CGNC:4843Inparanoid, OMA
Anole lizard100564829carscysteinyl-tRNA synthetase28377Inparanoid, OMA, EggNOG
Xenopus496832carscysteinyl-tRNA synthetase8364XB-GENE-5825933Inparanoid, OMA, EggNOG
Zebrafish368284carscysteinyl-tRNA synthetase7955ZDB-GENE-030328-29Inparanoid, OMA
C. elegans171821cars-1Cysteinyl Amino-acyl tRNA Synthetase6239Inparanoid, OMA
Fruitfly36784CysRSCysteinyl-tRNA synthetase7227FBgn0027091Inparanoid, OMA, EggNOG
S.cerevisiae855474YNL247Wcysteine--tRNA ligase4932S000005191Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    aminoacyl-tRNA synthetase    /    Cysteine--tRNA ligase, cytoplasmic
protein    /    nucleic acid binding    /    RNA binding protein    /    Cysteine--tRNA ligase, cytoplasmic
DTO Classes
protein    /    Enzyme    /    Ligase    /    Aminoacyl-tRNA synthetase    /    Cysteine--tRNA ligase, cytoplasmic

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source