CYP7A1

DescriptionCholesterol 7-alpha-monooxygenase

Gene and Protein Information

Gene ID1581
Uniprot Accession IDs P78454 Q3MIL8 Q7KZ19
Ensembl ID ENSP00000301645
Symbol CYP7 CP7A CYP7 CYPVII
FamilyBelongs to the cytochrome P450 family.
Sequence
MMTTSLIWGIAIAACCCLWLILGIRRRQTGEPPLENGLIPYLGCALQFGANPLEFLRANQRKHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHFATSAKAFGHRSIDPMDGNTTENINDTFIKTLQGHALNSLTESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYRVMFEAGYLTIFGRDLTRRDTQKAHILNNLDNFKQFDKVFPALVAGLPIHMFRTAHNAREKLAESLRHENLQKRESISELISLRMFLNDTLSTFDDLEKAKTHLVVLWASQANTIPATFWSLFQMIRNPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVLDSIIKESLRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELELIEGQAKCPPLDQSRAGLGILPPLNDIEFKYKFKHL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp464191CYP7A1cytochrome P450 family 7 subfamily A member 19598VGNC:6563OMA, EggNOG
Macaque698127CYP7A1cytochrome P450, family 7, subfamily A, polypeptide 19544Inparanoid, OMA, EggNOG
Mouse13122Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 110090MGI:106091Inparanoid, OMA, EggNOG
Rat25428Cyp7a1cytochrome P450 family 7 subfamily A member 110116RGD:2482Inparanoid, OMA, EggNOG
Dog486962CYP7A1cytochrome P450 family 7 subfamily A member 19615VGNC:50378Inparanoid, OMA, EggNOG
Horse100052888LOC100052888cholesterol 7-alpha-monooxygenase9796OMA, EggNOG
Cow510507CYP7A1cytochrome P450, family 7, subfamily A, polypeptide 19913Inparanoid, OMA, EggNOG
Pig448985CYP7A1cytochrome P450, family 7, subfamily A, polypeptide 19823Inparanoid, OMA, EggNOG
Opossum100022261CYP7A1cholesterol 7-alpha hydroxylase13616Inparanoid, OMA, EggNOG
Platypus100079392LOC100079392cholesterol 7-alpha-monooxygenase9258OMA, EggNOG
Anole lizard100562614LOC100562614cholesterol 7-alpha-monooxygenase28377OMA, EggNOG
Xenopus100488670cyp7a1cytochrome P450 family 7 subfamily A member 18364XB-GENE-485170Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    oxidoreductase    /    oxygenase    /    Cholesterol 7-alpha-monooxygenase
DTO Classes
protein    /    Enzyme    /    Oxidoreductase    /    Oxygenase    /    Cholesterol 7-alpha-monooxygenase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source