Protein or Target Summary
Isoleucine--tRNA ligase, mitochondrial
| Gene ID | 55699 |
|---|---|
| uniprot | Q9NSE4 |
| Gene Name | IARS2 |
| Ensernbl ID | ENSP00000355889 |
| Family | Belongs to the class-I aminoacyl-tRNA synthetase family. |
| Sequence | MRWGLRPRGPGAAALATARSLWGTPRLPCSPGWQGATKRLLVRSVSGASNHQPNSNSGRYRDTVLLPQTSFPMKLLGRQQPDTELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDGVFTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFINITDIKTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSGTSWSYVLPGPDQRADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYKVITVIEPGLLFEIIEMLQSEETSSTSQLNELMMASESTLLAQEPREMTADVIELKGKFLINLEGGDIREESSYKVIVMPTTKEKCPRCWKYTAESSDTLCPRCAEVVSGK Show more |
Gene and Protein Information
| Species | Gene ID | Gene Symbol | Gene Name | Uniprot |
|---|---|---|---|---|
| HUMAN | 55699 | IARS2 | Isoleucine--tRNA ligase, mitochondrial | Q9NSE4 |
| MOUSE | Iars2 | Iars2 protein | Q810V2 | |
| MOUSE | 381314 | Iars2 | Isoleucine--tRNA ligase, mitochondrial | E9PWN3 |
| MOUSE | Iars2 | Uncharacterized protein | Q8BIL6 | |
| MOUSE | Iars2 | Iars2 protein | Q8R2M5 | |
| MOUSE | Iars2 | Uncharacterized protein | Q8C1P9 | |
| MOUSE | Iars2 | Isoleucine--tRNA ligase, mitochondrial | E9PWN2 | |
| MOUSE | 381314 | Iars2 | Isoleucine--tRNA ligase, mitochondrial | Q8BIJ6 |
| RAT | Iars2 | Isoleucyl-tRNA synthetase 2, mitochondrial | A0A0G2K150 | |
| RAT | Iars2 | Isoleucyl-tRNA synthetase 2, mitochondrial | D4A8P9 | |
| RAT | Iars2 | Isoleucyl-tRNA synthetase 2, mitochondrial | A0A0G2K261 |
Protein Classes
PANTHER Classes
protein / ligase / aminoacyl-tRNA synthetase / Isoleucine--tRNA ligase, mitochondrial
protein / ligase / aminoacyl-tRNA synthetase / Isoleucine--tRNA ligase, mitochondrial
DTO Classes
protein / Enzyme / Ligase / Aminoacyl-tRNA synthetase / Isoleucine--tRNA ligase, mitochondrial
protein / Enzyme / Ligase / Aminoacyl-tRNA synthetase / Isoleucine--tRNA ligase, mitochondrial
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|
Source: DataSourcesLicenses.xlsx