IARS2

Description	Isoleucine--tRNA ligase, mitochondrial

Gene and Protein Information

Gene ID	55699
Uniprot Accession IDs	B2RPG8 Q1M2P9 Q6PI85 Q7L439 Q86WU9 Q96D91 Q9H9Q8 Q9NW42
Ensembl ID	ENSP00000355889
Symbol	ILERS CAGSSS
Family	Belongs to the class-I aminoacyl-tRNA synthetase family.
Sequence	MRWGLRPRGPGAAALATARSLWGTPRLPCSPGWQGATKRLLVRSVSGASNHQPNSNSGRYRDTVLLPQTSFPMKLLGRQQPDTELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDGVFTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFINITDIKTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSGTSWSYVLPGPDQRADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYKVITVIEPGLLFEIIEMLQSEETSSTSQLNELMMASESTLLAQEPREMTADVIELKGKFLINLEGGDIREESSYKVIVMPTTKEKCPRCWKYTAESSDTLCPRCAEVVSGK Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Mouse	381314	Iars2	isoleucine-tRNA synthetase 2, mitochondrial	10090	MGI:1919586	Inparanoid, OMA
Dog	478963	IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	9615	VGNC:41850	Inparanoid, OMA
Horse	100049915	IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	9796	VGNC:18922	Inparanoid, OMA
Cow	533057	IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	9913	VGNC:30019	Inparanoid, OMA
Opossum	100024337	IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	13616		Inparanoid, OMA
Platypus	100080817	IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	9258		Inparanoid, OMA
Chicken	421346	IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	9031	CGNC:7282	Inparanoid, OMA
Anole lizard	100559437	iars2	isoleucyl-tRNA synthetase 2, mitochondrial	28377		Inparanoid, OMA
Zebrafish	100001219	iars2	isoleucyl-tRNA synthetase 2, mitochondrial	7955	ZDB-GENE-030616-608	Inparanoid, OMA
S.cerevisiae	856067	ISM1	isoleucine--tRNA ligase ISM1	4932	S000005961	Inparanoid, OMA

PANTHER Classes
protein / ligase / aminoacyl-tRNA synthetase / Isoleucine--tRNA ligase, mitochondrial

DTO Classes
protein / Enzyme / Ligase / Aminoacyl-tRNA synthetase / Isoleucine--tRNA ligase, mitochondrial

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Name	Specifications	Species reactivity	species	Application	View Details

Name	Disease Type	Mondoid

Data Source	Name	Explore more targets	Explore in Source