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CYP1A2

DescriptionCytochrome P450 1A2

Gene and Protein Information

Gene ID1544
Uniprot Accession IDs P05177 Q16754 Q6NWU3 Q6NWU5 Q9BXX7 Q9UK49
Ensembl ID ENSP00000342007
Symbol CP12 CYPIA2 P3-450 P450(PA)
FamilyBelongs to the cytochrome P450 family.
Sequence
MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp735881CYP1A2cytochrome P450 family 1 subfamily A member 29598VGNC:13404Inparanoid, OMA
Mouse13077Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 210090MGI:88589Inparanoid, OMA, EggNOG
Rat24297Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 210116RGD:2459Inparanoid, OMA, EggNOG
Dog494010CYP1A2cytochrome P450 family 1 subfamily A member 29615VGNC:50333Inparanoid, OMA
Horse100062244CYP1A2cytochrome P450 family 1 subfamily A member 29796VGNC:50558Inparanoid, OMA
Pig100152910CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 29823Inparanoid, OMA
Xenopus100037911cyp1a1cytochrome P450 family 1 subfamily A member 18364XB-GENE-990173Inparanoid, OMA
Zebrafish140634cyp1acytochrome P450, family 1, subfamily A7955ZDB-GENE-011219-1Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    oxidoreductase    /    oxygenase    /    Cytochrome P450 1A2
DTO Classes
protein    /    Enzyme    /    Oxidoreductase    /    Oxygenase    /    Cytochrome P450 1A2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

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NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid
      medulloblastoma, large-cell6269Expression AtlasMONDO:0002791
      osteosarcoma7970Expression AtlasMONDO:0009807
      ovarian cancer8576Expression AtlasMONDO:0008170
      psoriasis6696Expression AtlasMONDO:0005083
      Atrophy0CTD
      Carcinoma, Hepatocellular980CTDMONDO:0007256
      Carcinoma, Squamous Cell125CTDMONDO:0005096
      Chemical and Drug Induced Liver Injury338CTDMONDO:0005359
      Cholestasis149CTDMONDO:0001751
      Colorectal Neoplasms703CTDMONDO:0005575

      Bibliography

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