FLT4

DescriptionVascular endothelial growth factor receptor 3

Gene and Protein Information

Gene ID2324
Uniprot Accession IDs A8K6L4 B5A926 Q16067 Q86W07 Q86W08 VEGFR-3
Ensembl ID ENSP00000261937
Symbol VEGFR3 PCL FLT-4 FLT41 LMPH1A LMPHM1 VEGFR3 VEGFR-3
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Sequence
MQRGAALCLRLWLCLGLLDGLVSGYSMTPPTLNITEESHVIDTGDSLSISCRGQHPLEWAWPGAQEAPATGDKDSEDTGVVRDCEGTDARPYCKVLLLHEVHANDTGSYVCYYKYIKARIEGTTAASSYVFVRDFEQPFINKPDTLLVNRKDAMWVPCLVSIPGLNVTLRSQSSVLWPDGQEVVWDDRRGMLVSTPLLHDALYLQCETTWGDQDFLSNPFLVHITGNELYDIQLLPRKSLELLVGEKLVLNCTVWAEFNSGVTFDWDYPGKQAERGKWVPERRSQQTHTELSSILTIHNVSQHDLGSYVCKANNGIQRFRESTEVIVHENPFISVEWLKGPILEATAGDELVKLPVKLAAYPPPEFQWYKDGKALSGRHSPHALVLKEVTEASTGTYTLALWNSAAGLRRNISLELVVNVPPQIHEKEASSPSIYSRHSRQALTCTAYGVPLPLSIQWHWRPWTPCKMFAQRSLRRRQQQDLMPQCRDWRAVTTQDAVNPIESLDTWTEFVEGKNKTVSKLVIQNANVSAMYKCVVSNKVGQDERLIYFYVTTIPDGFTIESKPSEELLEGQPVLLSCQADSYKYEHLRWYRLNLSTLHDAHGNPLLLDCKNVHLFATPLAASLEEVAPGARHATLSLSIPRVAPEHEGHYVCEVQDRRSHDKHCHKKYLSVQALEAPRLTQNLTDLLVNVSDSLEMQCLVAGAHAPSIVWYKDERLLEEKSGVDLADSNQKLSIQRVREEDAGRYLCSVCNAKGCVNSSASVAVEGSEDKGSMEIVILVGTGVIAVFFWVLLLLIFCNMRRPAHADIKTGYLSIIMDPGEVPLEEQCEYLSYDASQWEFPRERLHLGRVLGYGAFGKVVEASAFGIHKGSSCDTVAVKMLKEGATASEHRALMSELKILIHIGNHLNVVNLLGACTKPQGPLMVIVEFCKYGNLSNFLRAKRDAFSPCAEKSPEQRGRFRAMVELARLDRRRPGSSDRVLFARFSKTEGGARRASPDQEAEDLWLSPLTMEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDVVKICDFGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEILGDLLQGRGLQEEEEVCMAPRSSQSSEEGSFSQVSTMALHIAQADAEDSPPSLQRHSLAARYYNWVSFPGCLARGAETRGSSRMKTFEEFPMTPTTYKGSVDNQTDSGMVLASEEFEQIESRHRQESGFSCKGPGQNVAVTRAHPDSQGRRRRPERGARGGQVFYNSEYGELSEPSEEDHCSPSARVTFFTDNSY
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp462339FLT4fms related tyrosine kinase 49598VGNC:6876OMA, EggNOG
Macaque716412FLT4fms related tyrosine kinase 49544Inparanoid, OMA, EggNOG
Mouse14257Flt4FMS-like tyrosine kinase 410090MGI:95561Inparanoid, OMA, EggNOG
Rat114110Flt4fms-related tyrosine kinase 410116RGD:621737Inparanoid, OMA, EggNOG
Dog481464FLT4fms related tyrosine kinase 49615VGNC:40910Inparanoid, OMA, EggNOG
Horse100066773FLT4fms related tyrosine kinase 49796VGNC:18069Inparanoid, OMA, EggNOG
Cow338031FLT4fms related tyrosine kinase 49913VGNC:29044OMA, EggNOG
Pig100518179FLT4fms related tyrosine kinase 49823OMA, EggNOG
Opossum100032078FLT4fms related tyrosine kinase 413616Inparanoid, EggNOG
Chicken395742FLT4fms related tyrosine kinase 49031CGNC:49452Inparanoid, OMA, EggNOG
Anole lizard100556373flt4fms related tyrosine kinase 428377Inparanoid, OMA
Xenopus100493801flt4fms related tyrosine kinase 48364XB-GENE-483183Inparanoid, OMA, EggNOG
Zebrafish30121flt4fms-related tyrosine kinase 47955ZDB-GENE-980526-326Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    VEGFR family    /    Vascular endothelial growth factor receptor 3

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source