YES1

DescriptionTyrosine-protein kinase Yes

Gene and Protein Information

Gene ID7525
Uniprot Accession IDs A6NLB3 D3DUH1
Ensembl ID ENSP00000462468
Symbol YES Yes c-yes HsT441 P61-YES
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Sequence
MGCIKSKENKSPAIKYRPENTPEPVSTSVSHYGAEPTTVSPCPSSSAKGTAVNFSSLSMTPFGGSSGVTPFGGASSSFSVVPSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp455322YES1YES proto-oncogene 1, Src family tyrosine kinase9598VGNC:10011OMA, EggNOG
Macaque697099YES1YES proto-oncogene 1, Src family tyrosine kinase9544Inparanoid, OMA, EggNOG
Mouse22612Yes1YES proto-oncogene 1, Src family tyrosine kinase10090MGI:99147Inparanoid, OMA, EggNOG
Rat24884Yes1YES proto-oncogene 1, Src family tyrosine kinase10116RGD:3977Inparanoid, OMA, EggNOG
Dog403917YES1YES proto-oncogene 1, Src family tyrosine kinase9615VGNC:48484Inparanoid, OMA
Horse100061075YES1YES proto-oncogene 1, Src family tyrosine kinase9796VGNC:25098Inparanoid, OMA
Cow507632YES1YES proto-oncogene 1, Src family tyrosine kinase9913VGNC:37022Inparanoid, OMA
Platypus100076997YES1YES proto-oncogene 1, Src family tyrosine kinase9258Inparanoid, OMA
Chicken396238YES1YES proto-oncogene 1, Src family tyrosine kinase9031CGNC:49713Inparanoid, OMA
Anole lizard100559457yes1YES proto-oncogene 1, Src family tyrosine kinase28377Inparanoid, OMA
Xenopus493548yes1YES proto-oncogene 1, Src family tyrosine kinase8364XB-GENE-495082Inparanoid, OMA
Zebrafish407620yes1YES proto-oncogene 1, Src family tyrosine kinase7955ZDB-GENE-050126-1Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    SRC family    /    Tyrosine-protein kinase yes

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source