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TH
| Description | Tyrosine 3-monooxygenase |
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Gene and Protein Information
| Gene ID | 7054 |
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| Uniprot Accession IDs | B7ZL70 B7ZL73 Q0PWM2 Q0PWM3 Q15585 Q15588 Q15589 Q2M3B4 |
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| Ensembl ID | ENSP00000370571 |
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| Symbol | TYH TYH DYT14 DYT5b |
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| Family | Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. |
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| Sequence | MPTPDATTPQAKGFRRAVSELDAKQAEAIMVRGQGAPGPSLTGSPWPGTAAPAASYTPTPRSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVRQVSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 450955 | TH | tyrosine hydroxylase | 9598 | VGNC:988 | OMA, EggNOG |
| Macaque | 721137 | TH | tyrosine hydroxylase | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 21823 | Th | tyrosine hydroxylase | 10090 | MGI:98735 | Inparanoid, OMA, EggNOG |
| Rat | 25085 | Th | tyrosine hydroxylase | 10116 | RGD:3853 | Inparanoid, OMA, EggNOG |
| Dog | 403444 | TH | tyrosine hydroxylase | 9615 | VGNC:47322 | Inparanoid, OMA, EggNOG |
| Cow | 280707 | TH | tyrosine hydroxylase | 9913 | VGNC:35816 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100561541 | th | tyrosine hydroxylase | 28377 | | Inparanoid, OMA |
| Xenopus | | th | tyrosine hydroxylase [Source:Xenbase;Acc:XB-GENE-992305] | 8364 | | OMA, EggNOG |
| Zebrafish | 30384 | th | tyrosine hydroxylase | 7955 | ZDB-GENE-990621-5 | Inparanoid, OMA |
| Fruitfly | 38746 | ple | pale | 7227 | FBgn0005626 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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