JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

IRAK4

Description	Interleukin-1 receptor-associated kinase 4

Gene and Protein Information

Gene ID	51135
Uniprot Accession IDs	Q69FE1 Q8TDF7 Q9Y589 IRAK-4
Ensembl ID	ENSP00000390651
Symbol	IPD1 REN64 IRAK-4 NY-REN-64
Family	Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
Sequence	MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSKEAITVQQKQMPFCDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	466962	IRAK4	interleukin 1 receptor associated kinase 4	9598	VGNC:5434	OMA, EggNOG
Macaque	700568	IRAK4	interleukin 1 receptor associated kinase 4	9544		Inparanoid, OMA, EggNOG
Mouse	266632	Irak4	interleukin-1 receptor-associated kinase 4	10090	MGI:2182474	Inparanoid, OMA, EggNOG
Rat	300177	Irak4	interleukin-1 receptor-associated kinase 4	10116	RGD:1305303	Inparanoid, OMA, EggNOG
Dog	486601	IRAK4	interleukin 1 receptor associated kinase 4	9615	VGNC:42089	Inparanoid, OMA, EggNOG
Horse	100054848	IRAK4	interleukin 1 receptor associated kinase 4	9796	VGNC:19128	Inparanoid, OMA, EggNOG
Cow	533692	IRAK4	interleukin 1 receptor associated kinase 4	9913	VGNC:30268	Inparanoid, OMA, EggNOG
Pig	100127166	IRAK4	interleukin 1 receptor associated kinase 4	9823		Inparanoid, OMA, EggNOG
Opossum	100019202	IRAK4	interleukin 1 receptor associated kinase 4	13616		Inparanoid, OMA, EggNOG
Chicken	417796	IRAK4	interleukin 1 receptor associated kinase 4	9031	CGNC:7297	Inparanoid, OMA, EggNOG
Anole lizard	100556834	irak4	interleukin 1 receptor associated kinase 4	28377		Inparanoid, OMA, EggNOG
Xenopus	733738	irak4	interleukin 1 receptor associated kinase 4	8364	XB-GENE-492219	Inparanoid, OMA, EggNOG
Zebrafish	393132	irak4	interleukin-1 receptor-associated kinase 4	7955	ZDB-GENE-040426-738	Inparanoid, OMA

DTO Classes
protein / Kinase / Protein kinase / TKL group / IRAK family / Interleukin-1 receptor-associated kinase 4

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Name	Specifications	Species reactivity	species	Application	View Details

Name	Disease Type	Mondoid

Data Source	Name	Explore more targets	Explore in Source