Protein or Target Summary

Ras GTPase-activating-like protein IQGAP1

Gene ID	8826
uniprot	P46940
Gene Name	IQGAP1
Ensernbl ID	ENSP00000268182
Sequence	MSAADEVDGLGVARPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNMKTELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRRIPADTFAALKNPNAMLVNLEEPLASTYQDILYQAKQDKMTNAKNRTENSERERDVYEELLTQAEIQGNINKVNTFSALANIDLALEQGDALALFRALQSPALGLRGLQQQNSDWYLKQLLSDKQQKRQSGQTDPLQKEELQSGVDAANSAAQQYQRRLAAVALINAAIQKGVAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQRQSPEHNLTHPELSVAVEMLSSVALINRALESGDVNTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNEFITWNDIQACVDHVNLVVQEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREKAQEIQDESAVLWLDEIQGGIWQSNKDTQEAQKFALGIFAINEAVESGDVGKTLSALRSPDVGLYGVIPECGETYHSDLAEAKKKKLAVGDNNSKWVKHWVKGGYYYYHNLETQEGGWDEPPNFVQNSMQLSREEIQSSISGVTAAYNREQLWLANEGLITRLQARCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLRSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMVVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQTACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYKSYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLLNKKFYGK Show more

Gene and Protein Information

Species	Gene ID	Gene Symbol	Gene Name	Uniprot
HUMAN	8826	IQGAP1	Ras GTPase-activating-like protein IQGAP1	P46940
MOUSE		Iqgap1	MKIAA0051 protein	Q6ZQK2
MOUSE		Iqgap1	Uncharacterized protein	Q8CDT3
MOUSE		Iqgap1	Uncharacterized protein	Q8BPA6
MOUSE		Iqgap1	Ras GTPase-activating-like protein IQGAP1	A0A0U1RPI2
MOUSE		Iqgap1	Ras GTPase-activating-like protein IQGAP1	A0A0U1RPU3
MOUSE	29875	Iqgap1	Uncharacterized protein	Q3TU98
MOUSE	29875	Iqgap1	Uncharacterized protein	Q3TPD2
MOUSE		Iqgap1	Uncharacterized protein	Q3TR56
MOUSE		Iqgap1	IQ motif containing GTPase activating protein 1	Q80UW7
MOUSE		Iqgap1	Uncharacterized protein	Q8CC64
MOUSE		Iqgap1	Ras GTPase-activating-like protein IQGAP1	A0A0U1RNG5
MOUSE		Iqgap1	Uncharacterized protein	Q9D408
MOUSE		Iqgap1	Iqgap1 protein	Q05CQ4
MOUSE		Iqgap1	Iqgap1 protein	Q8CGH5
MOUSE	29875	Iqgap1	Ras GTPase-activating-like protein IQGAP1	Q9JKF1
RAT		Iqgap1	Iqgap1 protein	B5DFH1
RAT	361598	Iqgap1	IQ motif containing GTPase activating protein 1 (Predicted), isoform CRA_b	G3V7Q7

Protein Classes

PANTHER Classes
protein / enzyme modulator / G-protein modulator / Ras GTPase-activating-like protein IQGAP1

DTO Classes
protein / Enzyme modulator / G-protein modulator / Ras GTPase-activating-like protein IQGAP1

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

Source: DataSourcesLicenses.xlsx