Protein or Target Summary
Insulin-degrading enzyme
| Gene ID | 3416 |
|---|---|
| uniprot | P14735 |
| Gene Name | IDE |
| Ensernbl ID | ENSP00000265986 |
| Family | Belongs to the peptidase M16 family. |
| Sequence | MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL Show more |
Gene and Protein Information
| Species | Gene ID | Gene Symbol | Gene Name | Uniprot |
|---|---|---|---|---|
| HUMAN | 3416 | IDE | Insulin-degrading enzyme | P14735 |
| MOUSE | Ide | Insulin degrading enzyme | Q8CGB9 | |
| MOUSE | IDE | Insulin degrading enzyme | G8FSY5 | |
| MOUSE | Ide | Insulin-degrading enzyme | F6RPJ9 | |
| MOUSE | Ide | Uncharacterized protein | Q8CE37 | |
| MOUSE | Ide | Insulin-degrading enzyme | Q9JHR7 | |
| RAT | 25700 | Ide | Insulin-degrading enzyme | A0A0G2K7Q7 |
| RAT | 25700 | Ide | Insulin-degrading enzyme | P35559 |
Protein Classes
PANTHER Classes
protein / metalloprotease / Insulin-degrading enzyme
protein / protease / Insulin-degrading enzyme
protein / hydrolase / Insulin-degrading enzyme
protein / metalloprotease / Insulin-degrading enzyme
protein / protease / Insulin-degrading enzyme
protein / hydrolase / Insulin-degrading enzyme
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|
Source: TCRDv6_DataSourcesLicenses.xlsx