HIPK3

Description	Homeodomain-interacting protein kinase 3

Gene and Protein Information

Gene ID	10114
Uniprot Accession IDs	O14632 Q2PBG4 Q2PBG5 Q92632 Q9HAS2
Ensembl ID	ENSP00000304226
Symbol	DYRK6 FIST3 PKY PKY YAK1 DYRK6 FIST3
Family	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
Sequence	MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGSAFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLEGPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTVMDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVKSCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSVVHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISCSNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEPGREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETSIRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGHDSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQPLIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASPCTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYTGFPLSPTKLSQYPYM Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	451109	HIPK3	homeodomain interacting protein kinase 3	9598	VGNC:1072	OMA, EggNOG
Macaque	693786	HIPK3	homeodomain interacting protein kinase 3	9544		OMA, EggNOG
Mouse	15259	Hipk3	homeodomain interacting protein kinase 3	10090	MGI:1314882	Inparanoid, OMA, EggNOG
Rat	83617	Hipk3	homeodomain interacting protein kinase 3	10116	RGD:619884	Inparanoid, OMA, EggNOG
Dog	475947	HIPK3	homeodomain interacting protein kinase 3	9615	VGNC:41695	Inparanoid, OMA, EggNOG
Horse	106781398	HIPK3	homeodomain interacting protein kinase 3	9796	VGNC:18793	Inparanoid, OMA, EggNOG
Cow	538866	HIPK3	homeodomain interacting protein kinase 3	9913	VGNC:29860	Inparanoid, OMA, EggNOG
Pig	100515770	HIPK3	homeodomain interacting protein kinase 3	9823		OMA, EggNOG
Opossum	100023199	HIPK3	homeodomain interacting protein kinase 3	13616		Inparanoid, OMA, EggNOG
Platypus	100074561	HIPK3	homeodomain interacting protein kinase 3	9258		Inparanoid, OMA, EggNOG
Chicken	421597	HIPK3	homeodomain interacting protein kinase 3	9031	CGNC:8888	Inparanoid, OMA, EggNOG
Anole lizard	100554793	hipk3	homeodomain interacting protein kinase 3	28377		Inparanoid, OMA, EggNOG
Xenopus	780181	hipk3	homeodomain interacting protein kinase 3	8364	XB-GENE-1010053	Inparanoid, OMA, EggNOG
Zebrafish	569156	hipk3b	homeodomain interacting protein kinase 3b	7955	ZDB-GENE-030131-82	Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    protein kinase    /    Homeodomain-interacting protein kinase 3
protein    /    non-receptor serine/threonine protein kinase    /    Homeodomain-interacting protein kinase 3
protein    /    non-receptor tyrosine protein kinase    /    Homeodomain-interacting protein kinase 3
protein    /    transferase    /    Homeodomain-interacting protein kinase 3
protein    /    kinase    /    Homeodomain-interacting protein kinase 3

DTO Classes
protein / Kinase / Protein kinase / CMGC group / DYRK family / HIPK subfamily / Homeodomain-interacting protein kinase 3

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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