IRAK1

DescriptionInterleukin-1 receptor-associated kinase 1

Gene and Protein Information

Gene ID3654
Uniprot Accession IDs D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2 IRAK-1
Ensembl ID ENSP00000358997
Symbol IRAK IRAK pelle
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
Sequence
MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHSGPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque699919IRAK1interleukin 1 receptor associated kinase 19544Inparanoid, OMA
Mouse16179Irak1interleukin-1 receptor-associated kinase 110090MGI:107420Inparanoid, OMA
Rat363520Irak1interleukin-1 receptor-associated kinase 110116RGD:1563841Inparanoid, OMA
Dog492247IRAK1interleukin 1 receptor associated kinase 19615VGNC:42087Inparanoid, OMA
Horse100059262IRAK1interleukin 1 receptor associated kinase 19796VGNC:19125Inparanoid, OMA
Cow533953IRAK1interleukin 1 receptor associated kinase 19913VGNC:30264Inparanoid, OMA
Pig396606IRAK1interleukin 1 receptor associated kinase 19823Inparanoid, OMA
Opossum100029477IRAK1interleukin 1 receptor associated kinase 113616Inparanoid, OMA
Anole lizard100563977irak1interleukin 1 receptor associated kinase 128377Inparanoid, OMA
Xenopus448357irak1interleukin 1 receptor associated kinase 18364XB-GENE-488193Inparanoid, OMA
Zebrafish569226irak1interleukin-1 receptor-associated kinase 17955ZDB-GENE-071116-5Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    IRAK family    /    Interleukin-1 receptor-associated kinase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source