CHUK
| Description | Inhibitor of nuclear factor kappa-B kinase subunit alpha |
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Gene and Protein Information
| Gene ID | 1147 |
|---|---|
| Uniprot Accession IDs | O14666 Q13132 Q5W0I4 Q92467 I-kappa-B kinase alpha |
| Ensembl ID | ENSP00000359424 |
| Symbol | IKKA TCF16 IKK1 IKKA IKBKA TCF16 NFKBIKA IKK-alpha |
| Family | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. |
| Sequence | MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMSGEVRFSSHLPQPNSLCSLVVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGISLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGVIGYLEDQIMSLHAEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQSSARSLVGSSLEGAVTPQTSAWLPPTSAEHDHSLSCVVTPQDGETSAQMIEENLNCLGHLSTIIHEANEEQGNSMMNLDWSWLTE Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 450673 | CHUK | conserved helix-loop-helix ubiquitous kinase | 9598 | VGNC:1627 | OMA, EggNOG |
| Macaque | 709511 | CHUK | conserved helix-loop-helix ubiquitous kinase | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 12675 | Chuk | conserved helix-loop-helix ubiquitous kinase | 10090 | MGI:99484 | Inparanoid, OMA, EggNOG |
| Rat | 309361 | Chuk | conserved helix-loop-helix ubiquitous kinase | 10116 | RGD:1306661 | Inparanoid, OMA, EggNOG |
| Dog | 477796 | CHUK | conserved helix-loop-helix ubiquitous kinase | 9615 | VGNC:39261 | Inparanoid, OMA, EggNOG |
| Horse | 100070393 | CHUK | conserved helix-loop-helix ubiquitous kinase | 9796 | VGNC:16541 | Inparanoid, OMA, EggNOG |
| Cow | 281073 | CHUK | conserved helix-loop-helix ubiquitous kinase | 9913 | VGNC:27354 | Inparanoid, OMA, EggNOG |
| Pig | 100135662 | CHUK | conserved helix-loop-helix ubiquitous kinase | 9823 | Inparanoid, OMA | |
| Opossum | 100027952 | CHUK | conserved helix-loop-helix ubiquitous kinase | 13616 | Inparanoid, EggNOG | |
| Platypus | CHUK | conserved helix-loop-helix ubiquitous kinase [Source:HGNC Symbol;Acc:HGNC:1974] | 9258 | OMA, EggNOG | ||
| Chicken | 423669 | CHUK | conserved helix-loop-helix ubiquitous kinase | 9031 | CGNC:52021 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100565922 | chuk | conserved helix-loop-helix ubiquitous kinase | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 549654 | chuk | conserved helix-loop-helix ubiquitous kinase | 8364 | XB-GENE-5910008 | Inparanoid, OMA |
| Zebrafish | 393287 | chuk | conserved helix-loop-helix ubiquitous kinase | 7955 | ZDB-GENE-040426-1069 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / non-receptor serine/threonine protein kinase / Inhibitor of nuclear factor kappa-b kinase subunit alpha
protein / protein kinase / Inhibitor of nuclear factor kappa-b kinase subunit alpha
protein / transferase / Inhibitor of nuclear factor kappa-b kinase subunit alpha
protein / kinase / Inhibitor of nuclear factor kappa-b kinase subunit alpha
protein / non-receptor serine/threonine protein kinase / Inhibitor of nuclear factor kappa-b kinase subunit alpha
protein / protein kinase / Inhibitor of nuclear factor kappa-b kinase subunit alpha
protein / transferase / Inhibitor of nuclear factor kappa-b kinase subunit alpha
protein / kinase / Inhibitor of nuclear factor kappa-b kinase subunit alpha
DTO Classes
protein / Kinase / Protein kinase / Other group / IKK family / Inhibitor of nuclear factor kappa-b kinase subunit alpha
protein / Kinase / Protein kinase / Other group / IKK family / Inhibitor of nuclear factor kappa-b kinase subunit alpha
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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