MDM2

DescriptionE3 ubiquitin-protein ligase Mdm2

Gene and Protein Information

Gene ID4193
Uniprot Accession IDs A6NL51 A8K2S6 Q13226 Q13297 Q13298 Q13299 Q13300 Q13301 Q53XW0 Q71TW9 Q8WYJ1 Q8WYJ2 Q9UGI3 Q9UMT8
Ensembl ID ENSP00000258149
Symbol HDMX hdm2 ACTFS
FamilyBelongs to the MDM2/MDM4 family.
Sequence
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque718284MDM2MDM2 proto-oncogene9544Inparanoid, OMA
Mouse17246Mdm2transformed mouse 3T3 cell double minute 210090MGI:96952Inparanoid, OMA
Rat314856Mdm2MDM2 proto-oncogene10116RGD:1305332Inparanoid, OMA
Dog403693MDM2MDM2 proto-oncogene9615VGNC:43106Inparanoid, OMA
Horse100052084MDM2MDM2 proto-oncogene9796VGNC:20059Inparanoid, OMA
Cow540378MDM2MDM2 proto-oncogene9913VGNC:31336Inparanoid, OMA
Pig100125959MDM2MDM2 proto-oncogene9823Inparanoid, OMA
Platypus100080712MDM2MDM2 proto-oncogene9258Inparanoid, OMA
Chicken395609MDM2MDM2 proto-oncogene9031CGNC:7552Inparanoid, OMA
Anole lizard100556723mdm2MDM2 proto-oncogene28377Inparanoid, OMA
Xenopus394853mdm2MDM2 proto-oncogene8364XB-GENE-482711Inparanoid, OMA
Zebrafish30637mdm2MDM2 oncogene, E3 ubiquitin protein ligase7955ZDB-GENE-990415-153Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    chromatin/chromatin-binding protein    /    E3 ubiquitin-protein ligase Mdm2
DTO Classes
protein    /    Nucleic acid binding    /    DNA binding protein    /    Chromatin/chromatin-binding protein    /    E3 ubiquitin-protein ligase Mdm2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source