| Description | Inhibitor of nuclear factor kappa-B kinase subunit beta |
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Gene and Protein Information
| Gene ID | 3551 |
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| Uniprot Accession IDs | B4DZ30 B4E0U4 O75327 I-kappa-B-kinase beta |
| Ensembl ID | ENSP00000430684 |
| Symbol | IKKB IKK2 IKKB IMD15 IMD15A IMD15B NFKBIKB IKK-beta |
| Family | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. |
| Sequence | MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFTALDWSWLQTEEEEHSCLEQAS Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Macaque | 704683 | IKBKB | inhibitor of nuclear factor kappa B kinase subunit beta | 9544 | Inparanoid, EggNOG | |
| Mouse | 16150 | Ikbkb | inhibitor of kappaB kinase beta | 10090 | MGI:1338071 | Inparanoid, EggNOG |
| Rat | 84351 | Ikbkb | inhibitor of nuclear factor kappa B kinase subunit beta | 10116 | RGD:621375 | Inparanoid, EggNOG |
| Dog | 482839 | IKBKB | inhibitor of nuclear factor kappa B kinase subunit beta | 9615 | VGNC:51803 | Inparanoid, EggNOG |
| Cow | 281854 | IKBKB | inhibitor of nuclear factor kappa B kinase subunit beta | 9913 | Inparanoid, EggNOG | |
| Pig | 100101471 | IKBKB | inhibitor of nuclear factor kappa B kinase subunit beta | 9823 | Inparanoid, EggNOG | |
| Opossum | 100033031 | IKBKB | inhibitor of nuclear factor kappa B kinase subunit beta | 13616 | Inparanoid, EggNOG | |
| Platypus | 100078925 | IKBKB | inhibitor of nuclear factor kappa B kinase subunit beta | 9258 | Inparanoid, EggNOG |
Protein Classes
PANTHER Classes
protein / non-receptor serine/threonine protein kinase / Inhibitor of nuclear factor kappa-b kinase subunit beta
protein / protein kinase / Inhibitor of nuclear factor kappa-b kinase subunit beta
protein / transferase / Inhibitor of nuclear factor kappa-b kinase subunit beta
protein / kinase / Inhibitor of nuclear factor kappa-b kinase subunit beta
protein / non-receptor serine/threonine protein kinase / Inhibitor of nuclear factor kappa-b kinase subunit beta
protein / protein kinase / Inhibitor of nuclear factor kappa-b kinase subunit beta
protein / transferase / Inhibitor of nuclear factor kappa-b kinase subunit beta
protein / kinase / Inhibitor of nuclear factor kappa-b kinase subunit beta
DTO Classes
protein / Kinase / Protein kinase / Other group / IKK family / Inhibitor of nuclear factor kappa-b kinase subunit beta
protein / Kinase / Protein kinase / Other group / IKK family / Inhibitor of nuclear factor kappa-b kinase subunit beta
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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