FZD4

DescriptionFrizzled-4

Gene and Protein Information

Gene ID8322
Uniprot Accession IDs A8K9Q3 Q14C97 Q6S9E4 Fz-4
Ensembl ID ENSP00000434034
Symbol Fz4 EVR1 FEVR Fz-4 FzE4 GPCR hFz4 CD344 FZD4S
FamilyBelongs to the G-protein coupled receptor Fz/Smo family.
Sequence
MAWRGAGPSVPGAPGGVGLSLGLLLQLLLLLGPARGFGDEEERRCDPIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQPGEECHSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIRSNLQKDGTKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISNWALFRYSADDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNGWVKPGKGSETVV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp466732FZD4frizzled class receptor 49598VGNC:11783OMA, EggNOG
Macaque704754FZD4frizzled class receptor 49544Inparanoid, OMA, EggNOG
Mouse14366Fzd4frizzled class receptor 410090MGI:108520Inparanoid, OMA, EggNOG
Rat64558Fzd4frizzled class receptor 410116RGD:71017Inparanoid, OMA, EggNOG
Dog485149FZD4frizzled class receptor 49615VGNC:41032Inparanoid, OMA, EggNOG
Horse100050465FZD4frizzled class receptor 49796VGNC:18173Inparanoid, OMA, EggNOG
Cow445416FZD4frizzled class receptor 49913VGNC:29168Inparanoid, OMA, EggNOG
Pig100520319FZD4frizzled class receptor 49823Inparanoid, OMA
OpossumFZD4frizzled class receptor 4 [Source:HGNC Symbol;Acc:HGNC:4042]13616Inparanoid, EggNOG
Platypus100080994FZD4frizzled class receptor 49258Inparanoid, OMA, EggNOG
Chicken373887FZD4frizzled class receptor 49031CGNC:12957Inparanoid, OMA
Anole lizard100565823fzd4frizzled class receptor 428377Inparanoid, OMA
Xenopus100497693fzd4frizzled class receptor 48364XB-GENE-478210Inparanoid, OMA
Zebrafish30363fzd4frizzled class receptor 47955ZDB-GENE-990415-217Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    receptor    /    protease inhibitor    /    Frizzled-4
protein    /    receptor    /    signaling molecule    /    Frizzled-4
protein    /    receptor    /    G-protein coupled receptor    /    Frizzled-4
DTO Classes
protein    /    G-protein coupled receptor    /    Class F frizzled-type    /    Frizzled receptor    /    Frizzled-4

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source