GUCY2C

DescriptionHeat-stable enterotoxin receptor

Gene and Protein Information

Gene ID2984
Uniprot Accession IDs B2RMY6 STA receptor
Ensembl ID ENSP00000261170
Symbol GUC2C STAR GC-C STAR DIAR6 GUC2C MECIL MUCIL
FamilyBelongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Sequence
MKTLLLDLALWSLLFQPGWLSFSSQVSQNCHNGSYEISVLMMGNSAFAEPLKNLEDAVNEGLEIVRGRLQNAGLNVTVNATFMYSDGLIHNSGDCRSSTCEGLDLLRKISNAQRMGCVLIGPSCTYSTFQMYLDTELSYPMISAGSFGLSCDYKETLTRLMSPARKLMYFLVNFWKTNDLPFKTYSWSTSYVYKNGTETEDCFWYLNALEASVSYFSHELGFKVVLRQDKEFQDILMDHNRKSNVIIMCGGPEFLYKLKGDRAVAEDIVIILVDLFNDQYFEDNVTAPDYMKNVLVLTLSPGNSLLNSSFSRNLSPTKRDFALAYLNGILLFGHMLKIFLENGENITTPKFAHAFRNLTFEGYDGPVTLDDWGDVDSTMVLLYTSVDTKKYKVLLTYDTHVNKTYPVDMSPTFTWKNSKLPNDITGRGPQILMIAVFTLTGAVVLLLLVALLMLRKYRKDYELRQKKWSHIPPENIFPLETNETNHVSLKIDDDKRRDTIQRLRQCKYDKKRVILKDLKHNDGNFTEKQKIELNKLLQIDYYNLTKFYGTVKLDTMIFGVIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSSKTEVHGRLKSTNCVVDSRMVVKITDFGCNSILPPKKDLWTAPEHLRQANISQKGDVYSYGIIAQEIILRKETFYTLSCRDRNEKIFRVENSNGMKPFRPDLFLETAEEKELEVYLLVKNCWEEDPEKRPDFKKIETTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADRLNFMLLPRLVVKSLKEKGFVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDHIVDHHDVYKVETIGDAYMVASGLPKRNGNRHAIDIAKMALEILSFMGTFELEHLPGLPIWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHVSGSTIAILKRTECQFLYEVRGETYLKGRGNETTYWLTGMKDQKFNLPTPPTVENQQRLQAEFSDMIANSLQKRQAAGIRSQKPRRVASYKKGTLEYLQLNTTDKESTYF
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp473375GUCY2Cguanylate cyclase 2C9598VGNC:5410OMA, EggNOG
Mouse14917Gucy2cguanylate cyclase 2c10090MGI:106903Inparanoid, OMA, EggNOG
Rat25711Gucy2cguanylate cyclase 2C10116RGD:2771Inparanoid, OMA, EggNOG
Dog486671GUCY2Cguanylate cyclase 2C9615VGNC:41569Inparanoid, OMA, EggNOG
Horse100063810GUCY2Cguanylate cyclase 2C9796VGNC:18662Inparanoid, OMA, EggNOG
Cow282244GUCY2Cguanylate cyclase 2C9913VGNC:29722Inparanoid, OMA, EggNOG
PigPLBD1phospholipase B-like 1 precursor [Source:RefSeq peptide;Acc:NP_001231558]9823OMA, EggNOG
Opossum100016988GUCY2Cguanylate cyclase 2C13616Inparanoid, OMA, EggNOG
PlatypusGUCY2Cguanylate cyclase 2C [Source:HGNC Symbol;Acc:HGNC:4688]9258OMA, EggNOG
Chicken417968GUCY2Cguanylate cyclase 2C9031CGNC:8973Inparanoid, OMA, EggNOG
Anole lizard100563369gucy2cguanylate cyclase 2C28377Inparanoid, OMA, EggNOG
Xenopus100486678gucy2cguanylate cyclase 2C8364XB-GENE-952210Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    lyase    /    adenylate cyclase    /    Heat-stable enterotoxin receptor
protein    /    lyase    /    guanylate cyclase    /    Heat-stable enterotoxin receptor
DTO Classes
protein    /    Kinase    /    Protein kinase    /    RGC group    /    RGC family    /    Heat-stable enterotoxin receptor

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source