HIPK2

Description	Homeodomain-interacting protein kinase 2

Gene and Protein Information

Gene ID	28996
Uniprot Accession IDs	Q75MR7 Q8WWI4 Q9H2Y1 hHIPk2
Ensembl ID	ENSP00000385571
Symbol	PRO0593
Family	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
Sequence	MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTVSTSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADRREFIDLLKKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLTTVHNQAPSSTSATISLANPEVSILNYPSTLYQPSAASMAAVAQRSMPLQTGTAQICARPDPFQQALIVCPPGFQGLQASPSKHAGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQQAWPSGTQQILLPPAWQQLTGVATHTSVQHATVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPALLTGHVTLPAAQPLNVGVAHVMRQQPTSTTSSRKSKQHQSSVRNVSTCEVSSSQAISSPQRSKRVKENTPPRCAMVHSSPACSTSVTCGWGDVASSTTRERQRQTIVIPDTPSPTVSVITISSDTDEEEEQKHAPTSTVSKQRKNVISCVTVHDSPYSDSSSNTSPYSVQQRAGHNNANAFDTKGSLENHCTGNPRTIIVPPLKTQASEVLVECDSLVPVNTSHHSSSYKSKSSSNVTSTSGHSSGSSSGAITYRQQRPGPHFQQQQPLNLSQAQQHITTDRTGSHRRQQAYITPTMAQAPYSFPHNSPSHGTVHPHLAAAAAAAHLPTQPHLYTYTAPAALGSTGTVAHLVASQGSARHTVQHTAYPASIVHQVPVSMGPRVLPSPTIHPSQYPAQFAHQTYISASPASTVYTGYPLSPAKVNQYPYI Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	463772	HIPK2	homeodomain interacting protein kinase 2	9598	VGNC:4388	OMA, EggNOG
Macaque	716152	HIPK2	homeodomain interacting protein kinase 2	9544		Inparanoid, OMA, EggNOG
Mouse	15258	Hipk2	homeodomain interacting protein kinase 2	10090	MGI:1314872	Inparanoid, OMA, EggNOG
Rat	362342	Hipk2	homeodomain interacting protein kinase 2	10116	RGD:1309349	Inparanoid, OMA, EggNOG
Dog	482772	HIPK2	homeodomain interacting protein kinase 2	9615	VGNC:41694	Inparanoid, OMA, EggNOG
Horse	100064748	HIPK2	homeodomain interacting protein kinase 2	9796	VGNC:18792	Inparanoid, OMA, EggNOG
Cow		HIPK2	homeodomain interacting protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:14402]	9913		OMA, EggNOG
Opossum	100023480	HIPK2	homeodomain interacting protein kinase 2	13616		Inparanoid, OMA, EggNOG
Chicken	374138	HIPK2	homeodomain interacting protein kinase 2	9031	CGNC:49057	Inparanoid, OMA, EggNOG
Anole lizard	100566230	hipk2	homeodomain interacting protein kinase 2	28377		Inparanoid, OMA
Xenopus	780207	hipk2	homeodomain interacting protein kinase 2	8364	XB-GENE-958494	OMA, EggNOG
Zebrafish	557551	hipk2	homeodomain interacting protein kinase 2	7955	ZDB-GENE-031125-4	Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    protein kinase    /    Homeodomain-interacting protein kinase 2
protein    /    non-receptor serine/threonine protein kinase    /    Homeodomain-interacting protein kinase 2
protein    /    non-receptor tyrosine protein kinase    /    Homeodomain-interacting protein kinase 2
protein    /    transferase    /    Homeodomain-interacting protein kinase 2
protein    /    kinase    /    Homeodomain-interacting protein kinase 2

DTO Classes
protein / Kinase / Protein kinase / CMGC group / DYRK family / HIPK subfamily / Homeodomain-interacting protein kinase 2

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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