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Protein or Target Summary

3-hydroxy-3-methylglutaryl-coenzyme A reductase

Gene ID3156
uniprotP04035
Gene NameHMGCR
Ensernbl IDENSP00000287936
FamilyBelongs to the HMG-CoA reductase family.
Sequence
MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVTQKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN3156HMGCR3-hydroxy-3-methylglutaryl-coenzyme A reductaseP04035
MOUSEHMGCRHMGCR proteinQ61671
MOUSEHmgcr3-hydroxy-3-methylglutaryl-coenzyme A reductaseE9Q5H3
MOUSEHmgcr3-hydroxy-3-methylglutaryl-coenzyme A reductaseF7CA39
MOUSEHmgcr3-hydroxy-3-methylglutaryl-coenzyme A reductaseE9Q149
MOUSEHmgcr3-hydroxy-3-methylglutaryl coenzyme A reductaseQ6PB59
MOUSEHmgcr3-hydroxy-3-methylglutaryl-coenzyme A reductaseF6X166
MOUSEHmgcr3-hydroxy-3-methylglutaryl-coenzyme A reductaseE9PVG9
MOUSEHmgcr3-hydroxy-3-methylglutaryl-coenzyme A reductaseE9PY17
MOUSE15357Hmgcr3-hydroxy-3-methylglutaryl coenzyme A reductaseQ8BV96
MOUSEHmgcr3-hydroxy-3-methylglutaryl coenzyme A reductaseF2Z470
MOUSE15357Hmgcr3-hydroxy-3-methylglutaryl-coenzyme A reductaseQ01237
RAT25675Hmgcr3-hydroxy-3-methylglutaryl-coenzyme A reductaseP51639

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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