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HDAC6

DescriptionHistone deacetylase 6

Gene and Protein Information

Gene ID10013
Uniprot Accession IDs O94975 Q6NT75 Q7L3E5 Q96CY0 HD6
Ensembl ID ENSP00000334061
Symbol KIAA0901 HD6 JM21 CPBHM PPP1R90
FamilyBelongs to the histone deacetylase family. HD type 2 subfamily.
Sequence
MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque711363HDAC6histone deacetylase 69544Inparanoid, OMA, EggNOG
Mouse15185Hdac6histone deacetylase 610090MGI:1333752Inparanoid, OMA, EggNOG
Rat84581Hdac6histone deacetylase 610116RGD:619981Inparanoid, OMA
Rat108348065LOC108348065histone deacetylase 610116RGD:11442569OMA, EggNOG
Dog480907HDAC6histone deacetylase 69615VGNC:50630Inparanoid, OMA, EggNOG
Horse100062208HDAC6histone deacetylase 69796VGNC:50595Inparanoid, OMA, EggNOG
Cow513602HDAC6histone deacetylase 69913VGNC:50613Inparanoid, OMA, EggNOG
Pig100621798HDAC6histone deacetylase 69823OMA, EggNOG
Opossum100018936HDAC6histone deacetylase 613616Inparanoid, OMA, EggNOG
Anole lizardHDAC6histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064]28377Inparanoid, OMA
Xenopus100379853hdac6histone deacetylase 68364XB-GENE-5873935Inparanoid, OMA
Zebrafish565482hdac6histone deacetylase 67955ZDB-GENE-030131-3232Inparanoid, OMA
C. elegans177316hda-6Histone DeAcetylase6239Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Epigenetic regulator    /    Eraser    /    Histone deacetylase    /    HDAC class IIb    /    Histone deacetylase 6

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
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