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HDAC2

DescriptionHistone deacetylase 2

Gene and Protein Information

Gene ID3066
Uniprot Accession IDs Q92769 B3KRS5 B4DL58 E1P561 Q5SRI8 Q5SZ86 Q8NEH4 HD2
Ensembl ID ENSP00000430432
Symbol HD2 RPD3 YAF1 KDAC2
FamilyBelongs to the histone deacetylase family. HD type 1 subfamily.
Sequence
MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp462950HDAC2histone deacetylase 29598VGNC:11094OMA, EggNOG
Mouse15182Hdac2histone deacetylase 210090MGI:1097691Inparanoid, OMA
Rat84577Hdac2histone deacetylase 210116RGD:619976Inparanoid, OMA
Dog475035HDAC2histone deacetylase 29615VGNC:49101Inparanoid, OMA
Horse100072578HDAC2histone deacetylase 29796VGNC:51036Inparanoid, OMA
Cow407223HDAC2histone deacetylase 29913VGNC:50610Inparanoid, OMA
Opossum100022756HDAC2histone deacetylase 213616Inparanoid, OMA
Chicken395635HDAC2histone deacetylase 29031CGNC:11140Inparanoid, OMA
Anole lizard100566341hdac2histone deacetylase 228377Inparanoid, OMA
Xenopus447995hdac2histone deacetylase 28364XB-GENE-485807Inparanoid, OMA
C. elegans179959hda-1Histone deacetylase 16239Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    hydrolase    /    deacetylase    /    Histone deacetylase 2
protein    /    hydrolase    /    reductase    /    Histone deacetylase 2
protein    /    hydrolase    /    nucleic acid binding    /    Histone deacetylase 2
DTO Classes
protein    /    Epigenetic regulator    /    Eraser    /    Histone deacetylase    /    HDAC class I    /    Histone deacetylase 2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details
Recombinant HDAC2 AntibodyHuman,Mouse,Rat
  • IF/ICC
  • IHC
  • WB
In stock
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Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid
      group 3 medulloblastoma7142Expression AtlasMONDO:0007959
      lung cancer4468Expression AtlasMONDO:0008903
      medulloblastoma, large-cell6269Expression AtlasMONDO:0002791
      ovarian cancer8576Expression AtlasMONDO:0008170
      primitive neuroectodermal tumor3050Expression AtlasMONDO:0005462
      Carcinoma, Squamous Cell125CTDMONDO:0005096
      Cardiomegaly0CTD
      Endometriosis473CTDMONDO:0005133
      Leukemia, Myeloid18CTDMONDO:0004614
      Leukemia, Myeloid24CTDMONDO:0004643

      Bibliography

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